High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease

Familial Clustering of Aortic Size, Aneurysms, and Dissections in the Community

(2020) Jakob Raunsø et al.   CIRCULATION

Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program

(2020) Derek Klarin et al.   CIRCULATION

Characterization of the Rate of Aortic Dilation in Young Patients with Thoracic Aortic Aneurysm

(2020) Adam P. Wheeler et al.   PEDIATRIC CARDIOLOGY

Automated localization and quality control of the aorta in cine CMR can significantly accelerate processing of the UK Biobank population data

(2019) Luca Biasiolli et al.   PLoS One

Genetics of Thoracic and Abdominal Aortic Diseases

(2019) Amélie Pinard et al.   CIRCULATION RESEARCH

HAND2-mediated epithelial maintenance and integrity in cardiac outflow tract morphogenesis

(2019) Meng Xia et al.   DEVELOPMENT

Analysis of polygenic risk score usage and performance in diverse human populations

(2019) L. Duncan et al.   Nature Communications

Phenome-wide Burden of Copy-Number Variation in the UK Biobank

(2019) Matthew Aguirre et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Harmonizing Genetic Ancestry and Self-identified Race/Ethnicity in Genome-wide Association Studies

(2019) Huaying Fang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Three Novel Loci for Infant Head Circumference Identified by a Joint Association Analysis

(2019) Xiao-Lin Yang et al.   Frontiers in Genetics

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

(2018) Marie Verbanck et al.   NATURE GENETICS

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

(2018) Alvaro N. Barbeira et al.   Nature Communications

Clinical Validity of Genes for Heritable Thoracic Aortic Aneurysm and Dissection

(2018) Marjolijn Renard et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

Global Biobank Engine: enabling genotype-phenotype browsing for biobank summary statistics

(2018) Gregory McInnes et al.   BIOINFORMATICS

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults

(2018) Michael Inouye et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

(2018) Ayush Giri et al.   NATURE GENETICS

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

(2018) Nora Franceschini et al.   Nature Communications

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

(2017) Philipp S. Wild et al.   JOURNAL OF CLINICAL INVESTIGATION

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

(2017) Helen R Warren et al.   NATURE GENETICS

Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease

(2017) Pim van der Harst et al.   CIRCULATION RESEARCH

Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data

(2016) Huwenbo Shi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Phenotype of 7q11.23 duplication: A family clinical series

(2016) Beth A. Earhart et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Response to Statin Use and Aneurysm Risk in Patients With Bicuspid Aortic Valve Disease

(2016) Rodica Toganel et al.   CLINICAL CARDIOLOGY

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

7q11.23 Duplication syndrome: Physical characteristics and natural history

(2015) Colleen A. Morris et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Aortic Size Distribution in the General Population: Explaining the Size Paradox in Aortic Dissection

(2015) Vijayapraveena Paruchuri et al.   CARDIOLOGY

Statin Use and Aneurysm Risk in Patients With Bicuspid Aortic Valve Disease

(2015) Alexander P. Taylor et al.   CLINICAL CARDIOLOGY

Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors

(2015) Stephen Burgess et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Indications and imaging for aortic surgery: Size and other matters

(2015) John A. Elefteriades et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Novel MASP1 mutations are associated with an expanded phenotype in 3MC1 syndrome

(2015) Tahir Atik et al.   Orphanet Journal of Rare Diseases

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Thoracic Aortic Aneurysm and Dissection

(2014) Judith Z. Goldfinger et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Imputation and quality control steps for combining multiple genome-wide datasets

(2014) Shefali S. Verma et al.   Frontiers in Genetics

A Variant in LDLR Is Associated With Abdominal Aortic Aneurysm

(2013) Declan T. Bradley et al.   Circulation-Cardiovascular Genetics

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

(2013) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Genotype-phenotype analysis of 4q deletion syndrome: Proposal of a critical region

(2012) Eugen-Matthias Strehle et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Supravalvular Aortic Stenosis

(2012) Giuseppe Merla et al.   Circulation-Cardiovascular Genetics

What makes UK Biobank special?

(2012) Rory Collins   LANCET

Heart repair by reprogramming non-myocytes with cardiac transcription factors

(2012) Kunhua Song et al.   NATURE

Embryology and Imaging Review of Aortic Arch Anomalies

(2011) Jadranka Stojanovska et al.   JOURNAL OF THORACIC IMAGING

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

MASP1 Mutations in Patients with Facial, Umbilical, Coccygeal, and Auditory Findings of Carnevale, Malpuech, OSA, and Michels Syndromes

(2010) Asli Sirmaci et al.   AMERICAN JOURNAL OF HUMAN GENETICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Targeted deletion of Hand2 in cardiac neural crest-derived cells influences cardiac gene expression and outflow tract development

(2010) Kristen L. Holler et al.   DEVELOPMENTAL BIOLOGY

Epidemiology of thoracic aortic dissection

(2010) Scott A. LeMaire et al.   Nature Reviews Cardiology

Does Size Matter?

(2008) Frederick E. Dewey et al.   CIRCULATION