Peptide-based supramolecular hydrogels for local drug delivery

Injectable self-assembled bola-dipeptide hydrogels for sustained photodynamic prodrug delivery and enhanced tumor therapy

(2020) Qianli Zou et al.   JOURNAL OF CONTROLLED RELEASE

The entry of nanoparticles into solid tumours

(2020) Shrey Sindhwani et al.   NATURE MATERIALS

Biomaterial scaffold-based local drug delivery systems for cancer immunotherapy

(2020) Chen Yang et al.   Science Bulletin

Supramolecular prodrug hydrogelator as an immune booster for checkpoint blocker–based immunotherapy

(2020) Feihu Wang et al.   Science Advances

Tumour sensitization via the extended intratumoural release of a STING agonist and camptothecin from a self-assembled hydrogel

(2020) Feihu Wang et al.   Nature Biomedical Engineering

Overcoming negatively charged tissue barriers: Drug delivery using cationic peptides and proteins

(2020) Armin Vedadghavami et al.   Nano Today

Multifactorial Design of a Supramolecular Peptide Anti-IL-17 Vaccine Toward the Treatment of Psoriasis

(2020) Lucas S. Shores et al.   Frontiers in Immunology

Supramolecular Nanofibers with Superior Bioactivity to Insulin-Like Growth Factor-I

(2019) Yuna Shang et al.   NANO LETTERS

Sustained Release of Two Bioactive Factors from Supramolecular Hydrogel Promotes Periodontal Bone Regeneration

(2019) Jiali Tan et al.   ACS Nano

Enzyme‐Instructed Self‐Assembly (EISA) and Hydrogelation of Peptides

(2019) Jie Gao et al.   ADVANCED MATERIALS

Stimulus‐Responsive Hydrogel for Ophthalmic Drug Delivery

(2019) Deqing Lin et al.   MACROMOLECULAR BIOSCIENCE

Fine-Tuning the Linear Release Rate of Paclitaxel-Bearing Supramolecular Filament Hydrogels through Molecular Engineering

(2019) Rami W. Chakroun et al.   ACS Nano

Supramolecular peptide constructed by molecular Lego allowing programmable self-assembly for photodynamic therapy

(2019) Huangtianzhi Zhu et al.   Nature Communications

Carrier-Free Supramolecular Hydrogel Composed of Dual Drugs for Conquering Drug Resistance

(2019) Chunhua Ren et al.   ACS Applied Materials & Interfaces

pH-Switchable Antimicrobial Nanofiber Networks of Hydrogel Eradicate Biofilm and Rescue Stalled Healing in Chronic Wounds

(2019) Jianhao Wang et al.   ACS Nano

Octopus-like Flexible Vector for Noninvasive Intraocular Delivery of Short Interfering Nucleic Acids

(2019) Kuan Jiang et al.   NANO LETTERS

Nucleation and Growth of Amino Acid and Peptide Supramolecular Polymers through Liquid-Liquid Phase Separation

(2019) Chengqian Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Assembled Peptide Nanostructures Targeting Death Receptor 5 and Encapsulating Paclitaxel As a Multifunctional Cancer Therapy

(2019) Tyson J. Moyer et al.   ACS Biomaterials-Science & Engineering

Discovery of low-molecular weight anti-PD-L1 peptides for cancer immunotherapy

(2019) Hao Liu et al.   Journal for ImmunoTherapy of Cancer

A self-assembling peptide hydrogel-based drug co-delivery platform to improve tissue repair after ischemia-reperfusion injury

(2019) Shuyun Liu et al.   Acta Biomaterialia

Enhanced cellular uptake and nuclear accumulation of drug-peptide nanomedicines prepared by enzyme-instructed self-assembly

(2019) Chunhui Liang et al.   JOURNAL OF CONTROLLED RELEASE

Tumor Ablation and Therapeutic Immunity Induction by an Injectable Peptide Hydrogel

(2018) Honglin Jin et al.   ACS Nano

Ophthalmic gels: Past, present and future

(2018) Ali A. Al-Kinani et al.   ADVANCED DRUG DELIVERY REVIEWS

Supramolecular Nanofibers of Curcumin for Highly Amplified Radiosensitization of Colorectal Cancers to Ionizing Radiation

(2018) Huae Xu et al.   ADVANCED FUNCTIONAL MATERIALS

Injectable polypeptide hydrogel for dual-delivery of antigen and TLR3 agonist to modulate dendritic cells in vivo and enhance potent cytotoxic T-lymphocyte response against melanoma

(2018) Huijuan Song et al.   BIOMATERIALS

Zinc-ion-mediated self-assembly of forky peptides for prostate cancer-specific drug delivery

(2018) Mingtao Tao et al.   CHEMICAL COMMUNICATIONS

Control release of mitochondria-targeted antioxidant by injectable self-assembling peptide hydrogel ameliorated persistent mitochondrial dysfunction and inflammation after acute kidney injury

(2018) Meng Zhao et al.   DRUG DELIVERY

Polymer-based carriers for ophthalmic drug delivery

(2018) Julieta C. Imperiale et al.   JOURNAL OF CONTROLLED RELEASE

Self-assembly of a ibuprofen-peptide conjugate to suppress ocular inflammation

(2018) Xinxin Yu et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cell penetrating peptides: A concise review with emphasis on biomedical applications

(2018) Hossein Derakhshankhah et al.   BIOMEDICINE & PHARMACOTHERAPY

A Supramolecular Hydrogel for Spatial Release of Auxin to Pro-mote Plant Root Growth

(2018) Yaoxia Chen et al.   CHEMICAL COMMUNICATIONS

Stimuli-responsive peptide-based biomaterials as drug delivery systems

(2018) Afzal Shah et al.   CHEMICAL ENGINEERING JOURNAL

Investigations of Anti-Inflammatory Activity of a Peptide-Based Hydrogel Using Rat Air Pouch Model

(2018) Pramod K. Gavel et al.   ACS Applied Materials & Interfaces

Tandem Enzymatic Self-Assembly and Slow Release of Dexamethasone Enhances Its Antihepatic Fibrosis Effect

(2018) Wei Tang et al.   ACS Nano

Supramolecular Photothermal Nanomaterials as an Emerging Paradigm toward Precision Cancer Therapy

(2018) Luyang Zhao et al.   ADVANCED FUNCTIONAL MATERIALS

Enzyme-Instructed Supramolecular Self-Assembly with Anticancer Activity

(2018) Qingxin Yao et al.   ADVANCED MATERIALS

Biodegradable Amphipathic Peptide Hydrogels as Extended-Release System for Opioid Peptides

(2018) Charlotte Martin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Diversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy

(2017) Leila Peraro et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Supramolecular “Trojan Horse” for Nuclear Delivery of Dual Anticancer Drugs

(2017) Yanbin Cai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Substrate-Selective Enzyme-Catalysis Assembly Strategy for Oligopeptide Hydrogel-Assisted Combinatorial Protein Delivery

(2017) Tianyue Jiang et al.   NANO LETTERS

Intracellular coassembly boosts the anti-inflammation capacity of dexamethasone

(2017) Wei Tang et al.   Nanoscale

Paclitaxel nanoparticle awakens immune system to fight against cancer

(2017) Wei Tang et al.   Nanoscale

Cancer vaccines using supramolecular hydrogels of NSAID-modified peptides as adjuvants abolish tumorigenesis

(2017) Zhongyan Wang et al.   Nanoscale

Self-assembled RGD dehydropeptide hydrogels for drug delivery applications

(2017) Helena Vilaça et al.   Journal of Materials Chemistry B

Single Dose of Protein Vaccine with Peptide Nanofibers As Adjuvants Elicits Long-Lasting Antibody Titer

(2017) Chengbiao Yang et al.   ACS Biomaterials-Science & Engineering

Self-Assembling Peptide Nanofiber Hydrogels for Controlled Ocular Delivery of Timolol Maleate

(2017) Christina Karavasili et al.   ACS Biomaterials-Science & Engineering

Single Dose of Protein Vaccine with Peptide Nanofibers As Adjuvants Elicits Long-Lasting Antibody Titer

(2017) Chengbiao Yang et al.   ACS Biomaterials Science & Engineering

Self-Assembling Peptide Nanofiber Hydrogels for Controlled Ocular Delivery of Timolol Maleate

(2017) Christina Karavasili et al.   ACS Biomaterials Science & Engineering

Trace Solvent as a Predominant Factor To Tune Dipeptide Self-Assembly

(2016) Juan Wang et al.   ACS Nano

Self-assembling peptide-based delivery of therapeutics for myocardial infarction

(2016) Kristin M. French et al.   ADVANCED DRUG DELIVERY REVIEWS

Enzyme-Catalyzed Formation of Supramolecular Hydrogels as Promising Vaccine Adjuvants

(2016) Huaimin Wang et al.   ADVANCED FUNCTIONAL MATERIALS

A Powerful CD8+T-Cell Stimulating D-Tetra-Peptide Hydrogel as a Very Promising Vaccine Adjuvant

(2016) Zichao Luo et al.   ADVANCED MATERIALS

Fabrication of a Micellar Supramolecular Hydrogel for Ocular Drug Delivery

(2016) Zhaoliang Zhang et al.   BIOMACROMOLECULES

Targeting dendritic cells in lymph node with an antigen peptide-based nanovaccine for cancer immunotherapy

(2016) Yuan Qian et al.   BIOMATERIALS

MMP-9 triggered self-assembly of doxorubicin nanofiber depots halts tumor growth

(2016) Daniela Kalafatovic et al.   BIOMATERIALS

Treatment of hind limb ischemia using angiogenic peptide nanofibers

(2016) Vivek A. Kumar et al.   BIOMATERIALS

Electroconductive natural polymer-based hydrogels

(2016) Zhijun Shi et al.   BIOMATERIALS

Peptide self-assembly: thermodynamics and kinetics

(2016) Juan Wang et al.   CHEMICAL SOCIETY REVIEWS

Prolonged Ocular Retention of Mucoadhesive Nanoparticle Eye Drop Formulation Enables Treatment of Eye Diseases Using Significantly Reduced Dosage

(2016) Shengyan Liu et al.   MOLECULAR PHARMACEUTICS

Design and Synthesis of New Cell Penetrating Peptides: Diffusion and Distribution Inside the Cornea

(2016) Silvia Pescina et al.   MOLECULAR PHARMACEUTICS

Self-assembling bisphosphonates into nanofibers to enhance their inhibitory capacity on bone resorption

(2016) Anming Tang et al.   Nanoscale

Injectable peptide hydrogels for controlled-release of opioids

(2016) Charlotte Martin et al.   MedChemComm

Oligomeric Hydrogels Self-Assembled from Reduction-Controlled Condensation

(2015) Shuang Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dehydrodipeptide Hydrogelators Containing Naproxen N-Capped Tryptophan: Self-Assembly, Hydrogel Characterization, and Evaluation as Potential Drug Nanocarriers

(2015) Helena Vilaça et al.   BIOMACROMOLECULES

Nitric oxide releasing hydrogel enhances the therapeutic efficacy of mesenchymal stem cells for myocardial infarction

(2015) Xinpeng Yao et al.   BIOMATERIALS

Undefined role of mucus as a barrier in ocular drug delivery

(2015) Marika Ruponen et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Liver alkaline phosphatase: A missing link between choleresis and biliary inflammation

(2015) Raoul Poupon   HEPATOLOGY

Recent developments in ocular drug delivery

(2015) Hongming Chen   JOURNAL OF DRUG TARGETING

An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease

(2015) Sufeng Zhang et al.   Science Translational Medicine

Intramyocardial Delivery ofNotchLigand-Containing Hydrogels Improves Cardiac Function and Angiogenesis Following Infarction

(2015) Archana V. Boopathy et al.   TISSUE ENGINEERING PART A

Zinc-Triggered Hydrogelation of Self-assembled Small Molecules to Inhibit Bacterial Growth

(2015) Chao Xu et al.   Scientific Reports

MMP-9 triggered micelle-to-fibre transitions for slow release of doxorubicin

(2015) Daniela Kalafatovic et al.   Biomaterials Science

Self-Assembling Peptide of d-Amino Acids Boosts Selectivity and Antitumor Efficacy of 10-Hydroxycamptothecin

(2014) Jianfeng Liu et al.   ACS Applied Materials & Interfaces

in vitro and in vivo Evaluation of Novel Ocular Delivery System of 5-Fluorouracil Peptide Hydrogel

(2014)   ASIAN JOURNAL OF CHEMISTRY

A supramolecular hydrogelator of curcumin

(2014) Chengbiao Yang et al.   CHEMICAL COMMUNICATIONS

Long-term doxorubicin release from multiple stimuli-responsive hydrogels based on α-amino-acid residues

(2014) Mario Casolaro et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Penetratin, a Potentially Powerful Absorption Enhancer for Noninvasive Intraocular Drug Delivery

(2014) Chang Liu et al.   MOLECULAR PHARMACEUTICS

A Peptide-Based Nanofibrous Hydrogel as a Promising DNA Nanovector for Optimizing the Efficacy of HIV Vaccine

(2014) Yue Tian et al.   NANO LETTERS

Gradated assembly of multiple proteins into supramolecular nanomaterials

(2014) Gregory A. Hudalla et al.   NATURE MATERIALS

Self-assembly of peptides to nanostructures

(2014) Dindyal Mandal et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Photo-induced Reversible Structural Transition of Cationic Diphenylalanine Peptide Self-Assembly

(2014) Hongchao Ma et al.   Small

Fabrication of self-assembling peptide nanofiber hydrogels for myocardial repair

(2014) Xiao Yuan et al.   RSC Advances

pH-Responsive supramolecular hydrogels for codelivery of hydrophobic and hydrophilic anticancer drugs

(2014) Jing Yu et al.   RSC Advances

Titrating T-Cell Epitopes within Self-Assembled Vaccines Optimizes CD4+ Helper T Cell and Antibody Outputs

(2014) Rebecca R. Pompano et al.   Advanced Healthcare Materials

Nanofiber-Based Delivery of Therapeutic Peptides to the Brain

(2013) Mariarosa Mazza et al.   ACS Nano

Reversal of multidrug resistance by stimuli-responsive drug delivery systems for therapy of tumor

(2013) Qi Yin et al.   ADVANCED DRUG DELIVERY REVIEWS

Switchable Catalytic Activity: Selenium-Containing Peptides with Redox-Controllable Self-Assembly Properties

(2013) Xiaoming Miao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The use of self-adjuvanting nanofiber vaccines to elicit high-affinity B cell responses to peptide antigens without inflammation

(2013) Jianjun Chen et al.   BIOMATERIALS

Development and evaluation of fast forming nano-composite hydrogel for ocular delivery of diclofenac

(2013) XingYi Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Engineering synthetic vaccines using cues from natural immunity

(2013) Darrell J. Irvine et al.   NATURE MATERIALS

Disulfide bond reduction-triggered molecular hydrogels of folic acid–Taxol conjugates

(2013) Chengbiao Yang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Self-Adjuvanting Supramolecular Vaccine Carrying a Folded Protein Antigen

(2013) Gregory A. Hudalla et al.   Advanced Healthcare Materials

Nanoparticle and targeted systems for cancer therapy

(2012) Lisa Brannon-Peppas et al.   ADVANCED DRUG DELIVERY REVIEWS

Nanoparticles in cancer therapy and diagnosis

(2012) Irène Brigger et al.   ADVANCED DRUG DELIVERY REVIEWS

Sustained delivery of VEGF from designer self-assembling peptides improves cardiac function after myocardial infarction

(2012) Hai-dong Guo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Controlled release of dexamethasone from peptide nanofiber gels to modulate inflammatory response

(2012) Matthew J. Webber et al.   BIOMATERIALS

Combining adult stem cells and polymeric devices for tissue engineering in infarcted myocardium

(2012) Jean-Pierre Karam et al.   BIOMATERIALS

Cell-penetrating peptides: classes, origin, and current landscape

(2012) Francesca Milletti   DRUG DISCOVERY TODAY

Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers

(2012) Li Gan et al.   DRUG DISCOVERY TODAY

Stimulus-responsive nanopreparations for tumor targeting

(2012) Lin Zhu et al.   Integrative Biology

Nanomaterials for Ocular Drug Delivery

(2012) Shengyan Liu et al.   MACROMOLECULAR BIOSCIENCE

Instructive Nanofiber Scaffolds with VEGF Create a Microenvironment for Arteriogenesis and Cardiac Repair

(2012) Y.-D. Lin et al.   Science Translational Medicine

A peptide-based material for therapeutic carbon monoxide delivery

(2012) John B. Matson et al.   Soft Matter

Nanostructure-templated control of drug release from peptide amphiphile nanofiber gels

(2012) John B. Matson et al.   Soft Matter

A molecular hydrogel of a camptothecin derivative

(2012) Zhijian Song et al.   Biomaterials Science

Zinc-Triggered Hydrogelation of a Self-Assembling β-Hairpin Peptide

(2011) Christopher M. Micklitsch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The enhancement of mature vessel formation and cardiac function in infarcted hearts using dual growth factor delivery with self-assembling peptides

(2011) Ji Hyun Kim et al.   BIOMATERIALS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Drug release from hydrazone-containing peptide amphiphiles

(2011) John B. Matson et al.   CHEMICAL COMMUNICATIONS

Self-assembled nanospheres as a novel delivery system for taxol: a molecular hydrogel with nanosphere morphology

(2011) Huaimin Wang et al.   CHEMICAL COMMUNICATIONS

Supramolecular nanostructures that mimic VEGF as a strategy for ischemic tissue repair

(2011) M. J. Webber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-assembly of amphiphilic peptides

(2011) I. W. Hamley   Soft Matter

Peptide Hydrogel as an Intraocular Drug Delivery System for Inhibition of Postoperative Scarring Formation

(2010) Xiao-Ding Xu et al.   ACS Applied Materials & Interfaces

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Disulfide bond as a cleavable linker for molecular self-assembly and hydrogelation

(2010) Chunhua Ren et al.   CHEMICAL COMMUNICATIONS

Applications of peptide and protein-based materials in bionanotechnology

(2010) Roberto de la Rica et al.   CHEMICAL SOCIETY REVIEWS

Multi-component extracellular matrices based on peptide self-assembly

(2010) Joel H. Collier et al.   CHEMICAL SOCIETY REVIEWS

Novel Anisotropic Supramolecular Hydrogel with High Stability over a Wide pH Range†

(2010) Fan Zhao et al.   LANGMUIR

Thermoresponsive magnetic composite nanomaterials for multimodal cancer therapy

(2009) S. Purushotham et al.   Acta Biomaterialia

Collagen Structure and Stability

(2009) Matthew D. Shoulders et al.   Annual Review of Biochemistry

Enzyme-Instructed Molecular Self-assembly Confers Nanofibers and a Supramolecular Hydrogel of Taxol Derivative

(2009) Yuan Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tunable Mechanics of Peptide Nanofiber Gels

(2009) Megan A. Greenfield et al.   LANGMUIR

A biocompatible condensation reaction for controlled assembly of nanostructures in living cells

(2009) Gaolin Liang et al.   Nature Chemistry

Spotlight on hydrogels

(2009) Matthias P. Lutolf   NATURE MATERIALS

A self-assembling peptide acting as an immune adjuvant

(2009) J. S. Rudra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multifunctional magnetic nanoparticles for targeted imaging and therapy☆

(2008) J MCCARTHY et al.   ADVANCED DRUG DELIVERY REVIEWS

Hydrogel nanoparticles in drug delivery

(2008) Mehrdad Hamidi et al.   ADVANCED DRUG DELIVERY REVIEWS

Supramolecular gelling agents: can they be designed?

(2008) Parthasarathi Dastidar   CHEMICAL SOCIETY REVIEWS

Efficacy of Opioids for Chronic Pain

(2008) Jane C. Ballantyne et al.   CLINICAL JOURNAL OF PAIN

Recent Advances in Inorganic Nanoparticle-Based Drug Delivery Systems

(2008) Kunihiro Tsuchida et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Notch1 regulates the fate of cardiac progenitor cells

(2008) A. Boni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intradermal vaccine delivery: Will new delivery systems transform vaccine administration?

(2008) Paul Henri Lambert et al.   VACCINE

Challenges and solutions in topical ocular drug-delivery systems

(2008) Maryam Ali et al.   Expert Review of Clinical Pharmacology