CD146 is a Novel ANGPTL2 Receptor that Promotes Obesity by Manipulating Lipid Metabolism and Energy Expenditure

Adiponectin: A potential therapeutic target for metabolic syndrome

(2018) Abhijit A. Ghadge et al.   CYTOKINE & GROWTH FACTOR REVIEWS

CD146 interacts with galectin-3 to mediate endothelial cell migration

(2018) Zhongyu Zhang et al.   FEBS LETTERS

Mechanisms of Insulin Action and Insulin Resistance

(2018) Max C. Petersen et al.   PHYSIOLOGICAL REVIEWS

Enhanced ANGPTL2 expression in adipose tissues and its association with insulin resistance in obese women

(2018) Jimin Kim et al.   Scientific Reports

Combined inhibition of autophagy protein 5 and galectin-1 by thiodigalactoside reduces diet-induced obesity through induction of white fat browning

(2017) Hilal Ahmad Parray et al.   IUBMB LIFE

Galectin-3 interacts with the cell-surface glycoprotein CD146 (MCAM, MUC18) and induces secretion of metastasis-promoting cytokines from vascular endothelial cells

(2017) Florent Colomb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin action and resistance in obesity and type 2 diabetes

(2017) Michael P Czech   NATURE MEDICINE

CD146 coordinates brain endothelial cell–pericyte communication for blood–brain barrier development

(2017) Jianan Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DJ-1 maintains energy and glucose homeostasis by regulating the function of brown adipose tissue

(2017) Rong Wu et al.   Cell Discovery

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants

(2016)   LANCET

Pharmacological inhibition of galectin-1 by lactulose alleviates weight gain in diet-induced obese rats

(2016) Rajib Mukherjee et al.   LIFE SCIENCES

PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD

(2016) Barbara Gross et al.   Nature Reviews Endocrinology

Brown, Beige, and White: The New Color Code of Fat and Its Pharmacological Implications

(2015) Alexander Pfeifer et al.   Annual Review of Pharmacology and Toxicology

CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development

(2015) Tao Tu et al.   CELL RESEARCH

Galectin-3 Activates PPARγ and Supports White Adipose Tissue Formation and High-Fat Diet-Induced Obesity

(2015) Jung-Hwan Baek et al.   ENDOCRINOLOGY

Targeted inhibition of galectin 1 by thiodigalactoside dramatically reduces body weight gain in diet-induced obese rats

(2015) R Mukherjee et al.   INTERNATIONAL JOURNAL OF OBESITY

The cell biology of fat expansion

(2015) Joseph M. Rutkowski et al.   JOURNAL OF CELL BIOLOGY

Serum adiponectin and markers of endothelial dysfunction in stable angina pectoris patients undergoing coronary artery bypass grafting (CABG)

(2014) Anna Lisowska et al.   Advances in Medical Sciences

Targeting Endothelial CD146 Attenuates Colitis and Prevents Colitis-Associated Carcinogenesis

(2014) Shu Xing et al.   AMERICAN JOURNAL OF PATHOLOGY

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

Compartmentalization of cAMP Signaling in Adipogenesis, Lipogenesis, and Lipolysis

(2014) M. Rogne et al.   HORMONE AND METABOLIC RESEARCH

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2014) Marie Ng et al.   LANCET

Diverse roles of ANGPTL2 in physiology and pathophysiology

(2014) Tsuyoshi Kadomatsu et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A New Era in Brown Adipose Tissue Biology: Molecular Control of Brown Fat Development and Energy Homeostasis

(2013) Shingo Kajimura et al.   Annual Review of Physiology

Soluble CD146 in cerebrospinal fluid of active multiple sclerosis

(2013) H. Duan et al.   NEUROSCIENCE

Targeting endothelial CD146 attenuates neuroinflammation by limiting lymphocyte extravasation to the CNS

(2013) Hongxia Duan et al.   Scientific Reports

CD146 is a coreceptor for VEGFR-2 in tumor angiogenesis

(2012) T. Jiang et al.   BLOOD

CD146, a multi-functional molecule beyond adhesion

(2012) Zhaoqing Wang et al.   CANCER LETTERS

Tumor Cell-Derived Angiopoietin-like Protein ANGPTL2 Is a Critical Driver of Metastasis

(2012) M. Endo et al.   CANCER RESEARCH

Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity

(2012) Ana Ortega-Molina et al.   Cell Metabolism

The Involvement of CD146 and Its Novel Ligand Galectin-1 in Apoptotic Regulation of Endothelial Cells

(2012) Nathalie Jouve et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adaptive immunity in obesity and insulin resistance

(2012) Henrike Sell et al.   Nature Reviews Endocrinology

Angiopoietin-Like 2, a Circadian Gene, Improves Type 2 Diabetes Through Potentiation of Insulin Sensitivity in Mice Adipocytes

(2011) Masashi Kitazawa et al.   ENDOCRINOLOGY

Forming functional fat: a growing understanding of adipocyte differentiation

(2011) Ana G. Cristancho et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer

(2011) Q. Zeng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases

(2010) Tsuyoshi Kadomatsu et al.   FEBS Journal

Transcriptional control of preadipocyte determination by Zfp423

(2010) Rana K. Gupta et al.   NATURE

Brown adipose tissue—a new role in humans?

(2010) Martin E. Lidell et al.   Nature Reviews Endocrinology

The Nuclear Orphan Receptor COUP-TFII Plays an Essential Role in Adipogenesis, Glucose Homeostasis, and Energy Metabolism

(2009) Luoping Li et al.   Cell Metabolism

Angiopoietin-like Protein 2 Promotes Chronic Adipose Tissue Inflammation and Obesity-Related Systemic Insulin Resistance

(2009) Mitsuhisa Tabata et al.   Cell Metabolism

New developments in adipogenesis

(2009) Martina I. Lefterova et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Generation and Characterization of a Panel of Monoclonal Antibodies Against Distinct Epitopes of Human CD146

(2008) Ying Zhang et al.   HYBRIDOMA