A DYRK1B-dependent pathway suppresses rDNA transcription in response to DNA damage

Screen identifies DYRK1B network as mediator of transcription repression on damaged chromatin

(2020) Chao Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Double-strand breaks in ribosomal RNA genes activate a distinct signaling and chromatin response to facilitate nucleolar restructuring and repair

(2019) Lea M Korsholm et al.   NUCLEIC ACIDS RESEARCH

Nucleolar DNA Double-Strand Break Responses Underpinning rDNA Genomic Stability

(2019) Marjolein van Sluis et al.   TRENDS IN GENETICS

A cohesin/HUSH- and LINC-dependent pathway controls ribosomal DNA double-strand break repair

(2019) Aline Marnef et al.   GENES & DEVELOPMENT

Local inhibition of rRNA transcription without nucleolar segregation after targeted ion irradiation of the nucleolus

(2019) Christian Siebenwirth et al.   JOURNAL OF CELL SCIENCE

RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair

(2018) Liwei An et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual-utility NLS drives RNF169-dependent DNA damage responses

(2017) Liwei An et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breaks in the 45S rDNA Lead to Recombination-Mediated Loss of Repeats

(2016) Daniël O. Warmerdam et al.   Cell Reports

A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage

(2015) Marjolein van Sluis et al.   GENES & DEVELOPMENT

Nucleolar responses to DNA double-strand breaks

(2015) Dorthe Helena Larsen et al.   NUCLEIC ACIDS RESEARCH

ATM Dependent Silencing Links Nucleolar Chromatin Reorganization to DNA Damage Recognition

(2015) Shane M. Harding et al.   Cell Reports

The NBS1–Treacle complex controls ribosomal RNA transcription in response to DNA damage

(2014) Dorthe H. Larsen et al.   NATURE CELL BIOLOGY

Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response

(2014) Alberto Ciccia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ring Finger Protein RNF169 Antagonizes the Ubiquitin-dependent Signaling Cascade at Sites of DNA Damage

(2012) Jie Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks

(2012) Maria Poulsen et al.   JOURNAL OF CELL BIOLOGY

Tandem Protein Interaction Modules Organize the Ubiquitin-Dependent Response to DNA Double-Strand Breaks

(2012) Stephanie Panier et al.   MOLECULAR CELL