Immunotoxic role of Organophosphates: an unseen risk escalating SARS-CoV-2 pathogenicity

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Coronavirus infections and immune responses

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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

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Oxidative stress-mediated genotoxicity of malathion in human lymphocytes

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A pneumonia outbreak associated with a new coronavirus of probable bat origin

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Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak

(2020) Liangjun Chen et al.   Emerging Microbes & Infections

Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan

(2020) Jasper Fuk-Woo Chan et al.   Emerging Microbes & Infections

New Perspectives for Mucolytic, Anti-inflammatory and Adjunctive Therapy with 1,8-Cineole in COPD and Asthma: Review on the New Therapeutic Approach

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Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19

(2020) Hin Chu et al.   CLINICAL INFECTIOUS DISEASES

Self-reported Olfactory and Taste Disorders in Patients With Severe Acute Respiratory Coronavirus 2 Infection: A Cross-sectional Study

(2020) Andrea Giacomelli et al.   CLINICAL INFECTIOUS DISEASES

Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection

(2020) Lu Lin et al.   GUT

Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals

(2020) Ling Ni et al.   IMMUNITY

A review on the cleavage priming of the spike protein on coronavirus by angiotensin-converting enzyme-2 and furin

(2020) Anwarul Hasan et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

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(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

(2020) Ling Mao et al.   JAMA Neurology

Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China

(2020) Shaobo Shi et al.   JAMA Cardiology

C reactive protein impairs adaptive immunity in immune cells of patients with melanoma

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Hematological findings in coronavirus disease 2019: indications of progression of disease

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In Vitro Immunotoxicity of Organophosphate Flame Retardants in Human THP-1-Derived Macrophages

(2020) Xinyan Li et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses

(2020) Runhong Zhou et al.   IMMUNITY

Profile of natural anticoagulant, coagulant factor and anti-phospholipid antibody in critically ill COVID-19 patients

(2020) Yan Zhang et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

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(2020) L. Wang   MEDECINE ET MALADIES INFECTIEUSES

Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections

(2020) Quan-Xin Long et al.   NATURE MEDICINE

Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2

(2020) Matthias Thoms et al.   SCIENCE

Incidence of thrombotic complications in critically ill ICU patients with COVID-19

(2020) F.A. Klok et al.   THROMBOSIS RESEARCH

The laboratory tests and host immunity of COVID-19 patients with different severity of illness

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Geranium and Lemon Essential Oils and Their Active Compounds Downregulate Angiotensin-Converting Enzyme 2 (ACE2), a SARS-CoV-2 Spike Receptor-Binding Domain, in Epithelial Cells

(2020) K. J. Senthil Kumar et al.   Plants-Basel

Molecular docking study of potential phytochemicals and their effects on the complex of SARS-CoV2 spike protein and human ACE2

(2020) Anamika Basu et al.   Scientific Reports

Lifetime Pesticide Use and Antinuclear Antibodies in Male Farmers From the Agricultural Health Study

(2019) Christine G. Parks et al.   Frontiers in Immunology

Amelioration of fenitrothion induced oxidative DNA damage and inactivation of caspase-3 in the brain and spleen tissues of male rats by N-acetylcysteine

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Programmed necrotic cell death of macrophages: Focus on pyroptosis, necroptosis, and parthanatos

(2019) Nirmal Robinson et al.   Redox Biology

Potential risk of organophosphate exposure in male reproductive system of a non-target insect model Drosophila melanogaster

(2019) Moutushi Mandi et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Ameliorative effect of nanoencapsulated flavonoid against chlorpyrifos-induced hepatic oxidative damage and immunotoxicity in Wistar rats

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Acute renal involvement in organophosphate poisoning: histological and immunochemical investigations

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Pesticides and cardiotoxicity. Where do we stand?

(2018) Nikolaos Georgiadis et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Chronic exposure to acephate triggers ROS-mediated injuries at organismal and sub-organismal levels of Drosophila melanogaster

(2018) Prem Rajak et al.   Toxicology Research

Walnut Polyphenol Extract Protects against Fenitrothion-Induced Immunotoxicity in Murine Splenic Lymphocytes

(2018) Hong Liu et al.   Nutrients

Pesticide Exposure and Risk of Rheumatoid Arthritis among Licensed Male Pesticide Applicators in the Agricultural Health Study

(2017) Armando Meyer et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Protective effect of thymoquinone against diazinon-induced hematotoxicity, genotoxicity and immunotoxicity in rats

(2017) Gholam Hassan Danaei et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Exploring hazards of acute exposure of Acephate in Drosophila melanogaster and search for l -ascorbic acid mediated defense in it

(2017) Prem Rajak et al.   JOURNAL OF HAZARDOUS MATERIALS

Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness

(2017) Shilpa S. Iyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-shot ‘turn-off’ optical probe for rapid detection of paraoxon-ethyl pesticide on vegetable utilising fluorescence carbon dots

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Modulation of immunological activity on macrophages induced by diazinon

(2017) Nanako Ogasawara et al.   TOXICOLOGY

Increased Frequency of Rheumatoid Arthritis and Allergic Rhinitis among Pesticide Sprayers and Associations with Pesticide Use

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From immunotoxicity to carcinogenicity: the effects of carbamate pesticides on the immune system

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Aged garlic extract ameliorates immunotoxicity, hematotoxicity and impaired burn-healing in malathion- and carbaryl-treated male albino rats

(2016) Gamal Ramadan et al.   ENVIRONMENTAL TOXICOLOGY

Study of commonly used organophosphate pesticides that induced oxidative stress and apoptosis in peripheral blood lymphocytes of rats

(2016) A Ojha et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Modulation of macrophage functionality inducedin vitroby chlorpyrifos and carbendazim pesticides

(2016) Imen Helali et al.   Journal of Immunotoxicology

The SARS-coronavirus papain-like protease: Structure, function and inhibition by designed antiviral compounds

(2015) Yahira M. Báez-Santos et al.   ANTIVIRAL RESEARCH

Histopathological and genotoxic effects of chlorpyrifos in rats

(2015) Lobna Ezzi et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Dichlorvos Induced Autoimmune Hepatitis: A Case Report and Review of Literature

(2015) Su Xian Zhao et al.   Hepatitis Monthly

Simultaneous administration of hesperidin or garlic oil modulates diazinon-induced hemato- and immunotoxicity in rats

(2015) Imam Hassouna et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

The Nucleocapsid Protein of Coronaviruses Acts as a Viral Suppressor of RNA Silencing in Mammalian Cells

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Organophosphate Poisoning and Subsequent Acute Kidney Injury Risk

(2015) Feng-You Lee et al.   MEDICINE

Evaluation of the Protective Effect of Silibinin Against Diazinon Induced Hepatotoxicity and Free-Radical Damage in Rat Liver

(2015) Halil Beydilli et al.   Iranian Red Crescent Medical Journal

Cardiotoxicity in rabbits after a low-level exposure to diazinon, propoxur, and chlorpyrifos

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IL-17 and IL-22 serum levels in greenhouse workers exposed to pesticides

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Methoxychlor enhances degranulation of murine mast cells by regulating FcϵRI-mediated signal transduction

(2014) Sho Yasunaga et al.   Journal of Immunotoxicology

Nuclear NF-κB contributes to chlorpyrifos-induced apoptosis through p53 signaling in human neural precursor cells

(2014) Jeong Eun Lee et al.   NEUROTOXICOLOGY

Triazophos induced oxidative stress and histomorphological changes in liver and kidney of female albino rats

(2014) Dharmender Sharma et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Assessment of Cardiotoxicity and Effects of Malathion on the Early Development of Zebrafish (Danio Rerio) Using Computer Vision for Heart Rate Quantification

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Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Ion Channel Activity Promotes Virus Fitness and Pathogenesis

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Influence of organophosphate poisoning on human dendritic cells

(2013) Marina Schäfer et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation

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Immuno-pathologic effects of oral administration of chlorpyrifos in broiler chicks

(2013) Asim Shahzad et al.   Journal of Immunotoxicology

Organophosphate Poisoning-Induced Acute Renal Failure

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Pre-natal/juvenile chlorpyrifos exposure associated with immunotoxicity in adulthood in Swiss albino mice

(2012) Abhishek Kumar Singh et al.   Journal of Immunotoxicology

Immunotoxicity of the organochlorine pesticide methoxychlor in female ICR, BALB/c, and C3H/He mice

(2012) Koichi Hayashi et al.   Journal of Immunotoxicology

Immunotoxicity and disease resistance in Japanese quail (Corturnix coturnix japonica) exposed to malathion

(2011) S. Nain et al.   ECOTOXICOLOGY

Pesticide induced alterations in marrow physiology and depletion of stem and stromal progenitor population: An experimental model to study the toxic effects of pesticide

(2011) Sumanta Chatterjee et al.   ENVIRONMENTAL TOXICOLOGY

Levels of select organophosphates in human colostrum and mature milk samples in rural region of Faizabad district, Uttar Pradesh, India

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Prior exposure to immunosuppressive organophosphorus or organochlorine compounds aggravates the TH1- and TH2-type allergy caused by topical sensitization to 2,4-dinitrochlorobenzene and trimellitic anhydride

(2011) Tomoki Fukuyama et al.   Journal of Immunotoxicology

Destruction of Lymphoid Organ Architecture and Hepatitis Caused by CD4+ T Cells

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Protective effect of date palm fruit extract (Phoenix dactylifera L.) on dimethoate induced-oxidative stress in rat liver

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Effect of mucosal and systemic immunization with virus-like particles of severe acute respiratory syndrome coronavirus in mice

(2010) Baojing Lu et al.   IMMUNOLOGY

Malathion, Lindane, and Piperonyl Butoxide, Individually or in Combined Mixtures, Induce Immunotoxicity via Apoptosis in Murine Splenocytes In Vitro

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Assessment of phosphamidon-induced apoptosis in human peripheral blood mononuclear cells: Protective effects of N-acetylcysteine and curcumin

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Oxidative damage, hyperlipidemia and histological alterations of cardiac and skeletal muscles induced by different doses of diazinon in female rats

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A structural analysis of M protein in coronavirus assembly and morphology

(2010) Benjamin W. Neuman et al.   JOURNAL OF STRUCTURAL BIOLOGY

Early onset pneumonia in patients with cholinesterase inhibitor poisoning

(2010) Chen-Yu WANG et al.   RESPIROLOGY

Organophosphorous pesticide metabolite (DEDTP) induces changes in the activation status of human lymphocytes by modulating the interleukin 2 receptor signal transduction pathway

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Cardiac abnormalities in acute organophosphate poisoning

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Pesticide use and adult-onset asthma among male farmers in the Agricultural Health Study

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The cytotoxic effects of the organophosphates chlorpyrifos and diazinon differ from their immunomodulating effects

(2009) Gertie Janneke Oostingh et al.   Journal of Immunotoxicology

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

(2009) C. R. Baskin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of HSP27 and reduced glutathione in modulating malathion-induced apoptosis of human peripheral blood mononuclear cells: Ameliorating effect of N-acetylcysteine and curcumin

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