Bat-borne virus diversity, spillover and emergence

A novel coronavirus (2019-nCoV) causing pneumonia-associated respiratory syndrome

(2020) Shibo Jiang et al.   Cellular & Molecular Immunology

Seroreactive profiling of filoviruses in Chinese bats reveals extensive infection of diverse viruses

(2020) Chang Zhang et al.   JOURNAL OF VIROLOGY

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

(2020) Michael Letko et al.   Nature Microbiology

Viral zoonotic risk is homogenous among taxonomic orders of mammalian and avian reservoir hosts

(2020) Nardus Mollentze et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Predicting the global mammalian viral sharing network using phylogeography

(2020) Gregory F. Albery et al.   Nature Communications

Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host

(2019) Matae Ahn et al.   Nature Microbiology

Experimental Zika virus infection of Jamaican fruit bats (Artibeus jamaicensis) and possible entry of virus into brain via activated microglial cells

(2019) Ashley Malmlov et al.   PLoS Neglected Tropical Diseases

Clinical, Histopathologic, and Immunohistochemical Characterization of Experimental Marburg Virus Infection in A Natural Reservoir Host, the Egyptian Rousette Bat (Rousettus aegyptiacus)

(2019) Megan Jones et al.   Viruses-Basel

Bat Research Networks and Viral Surveillance: Gaps and Opportunities in Western Asia

(2019) Kendra Phelps et al.   Viruses-Basel

Immune System Modulation and Viral Persistence in Bats: Understanding Viral Spillover

(2019) Sonu Subudhi et al.   Viruses-Basel

A CRISPR activation screen identifies genes protecting from Zika virus infection

(2019) Anna Dukhovny et al.   JOURNAL OF VIROLOGY

Transmission of Nipah Virus — 14 Years of Investigations in Bangladesh

(2019) Birgit Nikolay et al.   NEW ENGLAND JOURNAL OF MEDICINE

A single-dose ChAdOx1-vectored vaccine provides complete protection against Nipah Bangladesh and Malaysia in Syrian golden hamsters

(2019) Neeltje van Doremalen et al.   PLoS Neglected Tropical Diseases

Prioritizing surveillance of Nipah virus in India

(2019) Raina K. Plowright et al.   PLoS Neglected Tropical Diseases

Long-term wildlife mortality surveillance in northern Congo: a model for the detection of Ebola virus disease epizootics

(2019) Eeva Kuisma et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

What is stirring in the reservoir? Modelling mechanisms of henipavirus circulation in fruit bat hosts

(2019) Emma E. Glennon et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Sampling to elucidate the dynamics of infections in reservoir hosts

(2019) Raina K. Plowright et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Curious Case of the Nidovirus Exoribonuclease: Its Role in RNA Synthesis and Replication Fidelity

(2019) Natacha S. Ogando et al.   Frontiers in Microbiology

Filovirus-reactive antibodies in humans and bats in Northeast India imply zoonotic spillover

(2019) Pilot Dovih et al.   PLoS Neglected Tropical Diseases

Temporal and spatial limitations in global surveillance for bat filoviruses and henipaviruses

(2019) Daniel J. Becker et al.   Biology Letters

The Egyptian Rousette Genome Reveals Unexpected Features of Bat Antiviral Immunity

(2018) Stephanie S. Pavlovich et al.   CELL

How many species of mammals are there?

(2018) Connor J Burgin et al.   JOURNAL OF MAMMALOGY

The Global Virome Project

(2018) Dennis Carroll et al.   SCIENCE

Rescue and characterization of recombinant cedar virus, a non-pathogenic Henipavirus species

(2018) Eric D. Laing et al.   Virology Journal

Environmental drivers of spatiotemporal foraging intensity in fruit bats and implications for Hendra virus ecology

(2018) John R. Giles et al.   Scientific Reports

Genome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication

(2018) Julianna Han et al.   Cell Reports

Pathogenesis of bat rabies in a natural reservoir: Comparative susceptibility of the straw-colored fruit bat (Eidolon helvum) to three strains of Lagos bat virus

(2018) Richard Suu-Ire et al.   PLoS Neglected Tropical Diseases

Bat Biology, Genomes, and the Bat1K Project: To Generate Chromosome-Level Genomes for All Living Bat Species

(2018) Emma C. Teeling et al.   Annual Review of Animal Biosciences

Serological Evidence of Bat SARS-Related Coronavirus Infection in Humans, China

(2018) Ning Wang et al.   VIROLOGICA SINICA

Changing resource landscapes and spillover of henipaviruses

(2018) Maureen K. Kessler et al.   Annals of the New York Academy of Sciences

Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin

(2018) Peng Zhou et al.   NATURE

Outbreaks in a Rapidly Changing Central Africa — Lessons from Ebola

(2018) Vincent J. Munster et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adaptive Evolution of MERS-CoV to Species Variation in DPP4

(2018) Michael Letko et al.   Cell Reports

The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses

(2018) Tracey Goldstein et al.   Nature Microbiology

Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication

(2018) Jyoti Batra et al.   CELL

Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis

(2018) Priya S. Shah et al.   CELL

Antibody-Mediated Virus Neutralization Is Not a Universal Mechanism of Marburg, Ebola, or Sosuga Virus Clearance in Egyptian Rousette Bats

(2018) Amy J Schuh et al.   JOURNAL OF INFECTIOUS DISEASES

Serological evidence of human infection by bat orthoreovirus in Singapore

(2018) Anna Uehara et al.   JOURNAL OF MEDICAL VIROLOGY

SARS-Like Coronavirus WIV1-CoV Does Not Replicate in Egyptian Fruit Bats (Rousettus aegyptiacus)

(2018) Neeltje van Doremalen et al.   Viruses-Basel

Characterization of a filovirus (Měnglà virus) from Rousettus bats in China

(2018) Xing-Lou Yang et al.   Nature Microbiology

Conditions affecting the timing and magnitude of Hendra virus shedding across pteropodid bat populations in Australia

(2017) D. J. PÁEZ et al.   EPIDEMIOLOGY AND INFECTION

Exploring the Human-Nipah Virus Protein-Protein Interactome

(2017) Luis Martinez-Gil et al.   JOURNAL OF VIROLOGY

Comparative Transcriptomics Highlights the Role of the Activator Protein 1 Transcription Factor in the Host Response to Ebolavirus

(2017) James W. Wynne et al.   JOURNAL OF VIROLOGY

Innate Immune Responses of Bat and Human Cells to Filoviruses: Commonalities and Distinctions

(2017) Ivan V. Kuzmin et al.   JOURNAL OF VIROLOGY

The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication

(2017) Preeti Bharaj et al.   JOURNAL OF VIROLOGY

Host and viral traits predict zoonotic spillover from mammals

(2017) Kevin J. Olival et al.   NATURE

Pathways to zoonotic spillover

(2017) Raina K. Plowright et al.   NATURE REVIEWS MICROBIOLOGY

Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA

(2017) François Ferron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus

(2017) S. J. Anthony et al.   mBio

Modelling filovirus maintenance in nature by experimental transmission of Marburg virus between Egyptian rousette bats

(2017) Amy J. Schuh et al.   Nature Communications

A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor

(2017) Brook E. Heaton et al.   Cell Reports

Protein–Protein Interactions in Virus–Host Systems

(2017) Anderson F. Brito et al.   Frontiers in Microbiology

Immunological Control of Viral Infections in Bats and the Emergence of Viruses Highly Pathogenic to Humans

(2017) Tony Schountz et al.   Frontiers in Immunology

Protective efficacy of a novel simian adenovirus vaccine against lethal MERS-CoV challenge in a transgenic human DPP4 mouse model

(2017) Vincent J. Munster et al.   npj Vaccines

Egyptian rousette bats maintain long-term protective immunity against Marburg virus infection despite diminished antibody levels

(2017) Amy J. Schuh et al.   Scientific Reports

Selective Bottlenecks Shape Evolutionary Pathways Taken during Mammalian Adaptation of a 1918-like Avian Influenza Virus

(2016) Louise H. Moncla et al.   Cell Host & Microbe

Influenza A virus PB1-F2 protein prolongs viral shedding in chickens lengthening the transmission window

(2016) Joe James et al.   JOURNAL OF GENERAL VIROLOGY

Broad and Temperature Independent Replication Potential of Filoviruses on Cells Derived From Old and New World Bat Species

(2016) Megan R. Miller et al.   JOURNAL OF INFECTIOUS DISEASES

A CRISPR screen defines a signal peptide processing pathway required by flaviviruses

(2016) Rong Zhang et al.   NATURE

Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

(2016) Caleb D. Marceau et al.   NATURE

A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors

(2016) Ryan J Park et al.   NATURE GENETICS

Contraction of the type I IFN locus and unusual constitutive expression ofIFN-αin bats

(2016) Peng Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid development of a DNA vaccine for Zika virus

(2016) K. A. Dowd et al.   SCIENCE

Hendra virus and Nipah virus animal vaccines

(2016) Christopher C. Broder et al.   VACCINE

Experimental Inoculation of Egyptian Fruit Bats (Rousettus aegyptiacus) with Ebola Virus

(2016) Janusz Paweska et al.   Viruses-Basel

Hendra virus ecology and transmission

(2016) Hume E Field   Current Opinion in Virology

Transmission or Within-Host Dynamics Driving Pulses of Zoonotic Viruses in Reservoir–Host Populations

(2016) Raina K. Plowright et al.   PLoS Neglected Tropical Diseases

A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles

(2016) Esther Ndungo et al.   mSphere

Chimpanzee Adenovirus Vaccine Provides Multispecies Protection against Rift Valley Fever

(2016) George M. Warimwe et al.   Scientific Reports

Replication and shedding of MERS-CoV in Jamaican fruit bats (Artibeus jamaicensis)

(2016) Vincent J. Munster et al.   Scientific Reports

De novo transcriptome reconstruction and annotation of the Egyptian rousette bat

(2015) Albert K. Lee et al.   BMC GENOMICS

Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding

(2015) Shashank Tripathi et al.   Cell Host & Microbe

Lack of Marburg Virus Transmission From Experimentally Infected to Susceptible In-Contact Egyptian Fruit Bats

(2015) Janusz T. Paweska et al.   JOURNAL OF INFECTIOUS DISEASES

Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination

(2015) Susanna K. P. Lau et al.   JOURNAL OF VIROLOGY

Glycosylation of Mouse DPP4 Plays a Role in Inhibiting Middle East Respiratory Syndrome Coronavirus Infection

(2015) Kayla M. Peck et al.   JOURNAL OF VIROLOGY

A Recently Discovered Pathogenic Paramyxovirus, Sosuga Virus, is Present in Rousettus aegyptiacus Fruit Bats at Multiple Locations in Uganda

(2015) Brian R. Amman et al.   JOURNAL OF WILDLIFE DISEASES

ORAL SHEDDING OF MARBURG VIRUS IN EXPERIMENTALLY INFECTED EGYPTIAN FRUIT BATS (ROUSETTUS AEGYPTIACUS)

(2015) Brian R. Amman et al.   JOURNAL OF WILDLIFE DISEASES

Intrinsic host restrictions to HIV-1 and mechanisms of viral escape

(2015) Viviana Simon et al.   NATURE IMMUNOLOGY

A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

(2015) Vineet D Menachery et al.   NATURE MEDICINE

Biannual birth pulses allow filoviruses to persist in bat populations

(2015) D. T. S. Hayman   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia

(2015) J. S. M. Sabir et al.   SCIENCE

Bats as ‘special’ reservoirs for emerging zoonotic pathogens

(2015) Cara E. Brook et al.   TRENDS IN MICROBIOLOGY

Experimental Inoculation of Egyptian Rousette Bats (Rousettus aegyptiacus) with Viruses of the Ebolavirus and Marburgvirus Genera

(2015) Megan Jones et al.   Viruses-Basel

The Role of the Antiviral APOBEC3 Gene Family in Protecting Chimpanzees against Lentiviruses from Monkeys

(2015) Lucie Etienne et al.   PLoS Pathogens

Bat Origins of MERS-CoV Supported by Bat Coronavirus HKU4 Usage of Human Receptor CD26

(2014) Qihui Wang et al.   Cell Host & Microbe

Mouse Dipeptidyl Peptidase 4 Is Not a Functional Receptor for Middle East Respiratory Syndrome Coronavirus Infection

(2014) A. S. Cockrell et al.   JOURNAL OF VIROLOGY

The effect of seasonal birth pulses on pathogen persistence in wild mammal populations

(2014) A. J. Peel et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Immunology of Bats and Their Viruses: Challenges and Opportunities

(2014) Tony Schountz   Viruses-Basel

Filoviruses in Bats: Current Knowledge and Future Directions

(2014) Kevin Olival et al.   Viruses-Basel

DBatVir: the database of bat-associated viruses

(2014) L. Chen et al.   Database-The Journal of Biological Databases and Curation

Host-Specific Parvovirus Evolution in Nature Is Recapitulated by In Vitro Adaptation to Different Carnivore Species

(2014) Andrew B. Allison et al.   PLoS Pathogens

Receptor recognition and cross-species infections of SARS coronavirus

(2013) Fang Li   ANTIVIRAL RESEARCH

EXPERIMENTAL RABIES VIRUS INFECTION OF BIG BROWN BATS (EPTESICUS FUSCUS)

(2013) Felix R. Jackson et al.   JOURNAL OF WILDLIFE DISEASES

Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor

(2013) Xing-Yi Ge et al.   NATURE

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

(2013) V. Stalin Raj et al.   NATURE

A Strategy To Estimate Unknown Viral Diversity in Mammals

(2013) S. J. Anthony et al.   mBio

New World Bats Harbor Diverse Influenza A Viruses

(2013) Suxiang Tong et al.   PLoS Pathogens

APOBEC3G Polymorphism as a Selective Barrier to Cross-Species Transmission and Emergence of Pathogenic SIV and AIDS in a Primate Host

(2013) Annabel Krupp et al.   PLoS Pathogens

Tacaribe Virus Causes Fatal Infection of An Ostensible Reservoir Host, the Jamaican Fruit Bat

(2012) A. Cogswell-Hawkinson et al.   JOURNAL OF VIROLOGY

Virological and Serological Findings in Rousettus aegyptiacus Experimentally Inoculated with Vero Cells-Adapted Hogan Strain of Marburg Virus

(2012) Janusz T. Paweska et al.   PLoS One

Cedar Virus: A Novel Henipavirus Isolated from Australian Bats

(2012) Glenn A. Marsh et al.   PLoS Pathogens

Seasonal Pulses of Marburg Virus Circulation in Juvenile Rousettus aegyptiacus Bats Coincide with Periods of Increased Risk of Human Infection

(2012) Brian R. Amman et al.   PLoS Pathogens

Pteropid Bats are Confirmed as the Reservoir Hosts of Henipaviruses: A Comprehensive Experimental Study of Virus Transmission

(2011) Kim Halpin et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Type III IFNs in Pteropid Bats: Differential Expression Patterns Provide Evidence for Distinct Roles in Antiviral Immunity

(2011) P. Zhou et al.   JOURNAL OF IMMUNOLOGY

Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

(2011) Marceline Côté et al.   NATURE

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

Urban habituation, ecological connectivity and epidemic dampening: the emergence of Hendra virus from flying foxes (Pteropus spp.)

(2011) R. K. Plowright et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Coronaviruses

(2011) Mark R. Denison et al.   RNA Biology

Date Palm Sap Linked to Nipah Virus Outbreak in Bangladesh, 2008

(2011) Muhammad Aziz Rahman et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

Host immunity to repeated rabies virus infection in big brown bats

(2010) A. S. Turmelle et al.   JOURNAL OF GENERAL VIROLOGY

Host Phylogeny Constrains Cross-Species Emergence and Establishment of Rabies Virus in Bats

(2010) D. G. Streicker et al.   SCIENCE

Endogenous Viral Elements in Animal Genomes

(2010) Aris Katzourakis et al.   PLoS Genetics

Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein

(2009) Rachel L. Kaletsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation of Genetically Diverse Marburg Viruses from Egyptian Fruit Bats

(2009) Jonathan S. Towner et al.   PLoS Pathogens

Interaction of severe acute respiratory syndrome-coronavirus and NL63 coronavirus spike proteins with angiotensin converting enzyme-2

(2008) A. C. Mathewson et al.   JOURNAL OF GENERAL VIROLOGY

Inhibition of Lassa and Marburg Virus Production by Tetherin

(2008) T. Sakuma et al.   JOURNAL OF VIROLOGY

Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by Tetherin

(2008) N. Jouvenet et al.   JOURNAL OF VIROLOGY

Emergence and control of infectious diseases in China

(2008) Longde Wang et al.   LANCET

Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice

(2008) M. M. Becker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reproduction and nutritional stress are risk factors for Hendra virus infection in little red flying foxes (Pteropus scapulatus)

(2008) R. K Plowright et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Induction and sequencing of Rousette bat interferon α and β genes

(2008) Tsutomu Omatsu et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Vaccinating the vampire bat Desmodus rotundus against rabies

(2008) M.F. Almeida et al.   VIRUS RESEARCH