Adropin regulates hepatic glucose production via PP2A/AMPK pathway in insulin‐resistant hepatocytes

The peptide hormone adropin regulates signal transduction pathways controlling hepatic glucose metabolism in a mouse model of diet-induced obesity

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Prevention and Management of Severe Hypoglycemia and Hypoglycemia Unawareness: Incorporating Sensor Technology

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Properties and functions of adipose tissue macrophages in obesity

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Adropin protects against liver injury in nonalcoholic steatohepatitis via the Nrf2 mediated antioxidant capacity

(2018) Xu Chen et al.   Redox Biology

TGF-β1/Smad3 Pathway Targets PP2A-AMPK-FoxO1 Signaling to Regulate Hepatic Gluconeogenesis

(2017) Hariom Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of hepatic glucose metabolism in health and disease

(2017) Max C. Petersen et al.   Nature Reviews Endocrinology

Liver AMP-Activated Protein Kinase Is Unnecessary for Gluconeogenesis but Protects Energy State during Nutrient Deprivation

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Liver-specific deletion of Ppp2cα enhances glucose metabolism and insulin sensitivity

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Inhibition of AMP Kinase by the Protein Phosphatase 2A Heterotrimer, PP2APpp2r2d

(2015) Biny K. Joseph et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular pathophysiology of hepatic glucose production

(2015) Kfir Sharabi et al.   MOLECULAR ASPECTS OF MEDICINE

CREB and FoxO1: two transcription factors for the regulation of hepatic gluconeogenesis

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Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

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cAMP-responsive Element-binding Protein (CREB)-regulated Transcription Coactivator 2 (CRTC2) Promotes Glucagon Clearance and Hepatic Amino Acid Catabolism to Regulate Glucose Homeostasis

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Sodium caprate augments the hypoglycemic effect of berberine via AMPK in inhibiting hepatic gluconeogenesis

(2012) Ming Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Adropin Deficiency Is Associated With Increased Adiposity and Insulin Resistance

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Using kinomics to delineate signaling pathways: Control of crtc2/torc2 by the ampk family

(2011) Accalia Fu et al.   CELL CYCLE

Free Fatty Acid-Induced PP2A Hyperactivity Selectively Impairs Hepatic Insulin Action on Glucose Metabolism

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FoxOs Function Synergistically to Promote Glucose Production

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AMPK-dependent Repression of Hepatic Gluconeogenesis via Disruption of CREB·CRTC2 Complex by Orphan Nuclear Receptor Small Heterodimer Partner

(2010) Ji-Min Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

(2010) Marc Foretz et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity

(2010) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis

(2009) Yiguo Wang et al.   NATURE

Identification of Adropin as a Secreted Factor Linking Dietary Macronutrient Intake with Energy Homeostasis and Lipid Metabolism

(2008) K. Ganesh Kumar et al.   Cell Metabolism

Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes

(2008) John W. Scott et al.   CHEMISTRY & BIOLOGY