Extracellular vesicles of carcinoma-associated fibroblasts creates a pre-metastatic niche in the lung through activating fibroblasts

Hypoxic BMSC-derived exosomal miRNAs promote metastasis of lung cancer cells via STAT3-induced EMT

(2019) Xina Zhang et al.   Molecular Cancer

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Aberrant low expression of p85α in stromal fibroblasts promotes breast cancer cell metastasis through exosome-mediated paracrine Wnt10b

(2017) Y Chen et al.   ONCOGENE

CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis

(2017) X W Chen et al.   ONCOGENE

Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane

(2017) Alexandros Glentis et al.   Nature Communications

Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis

(2017) Haiyang Zhang et al.   Nature Communications

Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche

(2017) Michael P. Plebanek et al.   Nature Communications

Epiregulin Promotes Lung Metastasis of Salivary Adenoid Cystic Carcinoma

(2017) Wen-Wen Yang et al.   Theranostics

Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases

(2017) Chen Rachman-Tzemah et al.   Cell Reports

Characteristics and Significance of the Pre-metastatic Niche

(2016) Yang Liu et al.   CANCER CELL

Tumor Exosomal RNAs Promote Lung Pre-metastatic Niche Formation by Activating Alveolar Epithelial TLR3 to Recruit Neutrophils

(2016) Yanfang Liu et al.   CANCER CELL

Cancer Tills the Premetastatic Field: Mechanistic Basis and Clinical Implications

(2016) A. R. Chin et al.   CLINICAL CANCER RESEARCH

Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness

(2016) Julie Leca et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatic carcinoma-associated fibroblasts enhance immune suppression by facilitating the generation of myeloid-derived suppressor cells

(2016) Y Deng et al.   ONCOGENE

Cytoplasmic GPER translocation in cancer-associated fibroblasts mediates cAMP/PKA/CREB/glycolytic axis to confer tumor cells with multidrug resistance

(2016) T Yu et al.   ONCOGENE

Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells

(2016) K E Richards et al.   ONCOGENE

Carcinoma-Associated Fibroblasts Lead the Invasion of Salivary Gland Adenoid Cystic Carcinoma Cells by Creating an Invasive Track

(2016) Jiao Li et al.   PLoS One

Proteomics characterization of exosome cargo

(2015) Kevin L. Schey et al.   METHODS

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

(2015) Wenchao Zhou et al.   NATURE CELL BIOLOGY

Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis

(2015) Miranda Y. Fong et al.   NATURE CELL BIOLOGY

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Extracellular Vesicles in Cancer: Exosomes, Microvesicles and the Emerging Role of Large Oncosomes

(2015) Valentina R. Minciacchi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

(2014) Basant Kumar Thakur et al.   CELL RESEARCH

Carcinoma-associated fibroblasts provide operational flexibility in metastasis

(2014) Olivier De Wever et al.   SEMINARS IN CANCER BIOLOGY

The pre-metastatic niche: finding common ground

(2013) Jaclyn Sceneay et al.   CANCER AND METASTASIS REVIEWS

Clinicopathological study of distant metastases of salivary adenoid cystic carcinoma

(2013) M. Gao et al.   INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci

(2013) Sachie Hiratsuka et al.   Nature Communications

Tumor cell and carcinoma-associated fibroblast interaction regulates matrix metalloproteinases and their inhibitors in oral squamous cell carcinoma

(2012) Alexandra Fullár et al.   EXPERIMENTAL CELL RESEARCH

Periostin in fibrillogenesis for tissue regeneration: periostin actions inside and outside the cell

(2011) Akira Kudo   CELLULAR AND MOLECULAR LIFE SCIENCES

Roles of Metalloproteases in Metastatic Niche

(2011) N. Rucci et al.   CURRENT MOLECULAR MEDICINE

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

(2010) M. Kowanetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche

(2009) Janine T. Erler et al.   CANCER CELL

Small-molecule inhibitors of integrin α2β1 that prevent pathological thrombus formation via an allosteric mechanism

(2009) Meredith W. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential impact of TGF-β and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion

(2008) Hannelore Denys et al.   CANCER LETTERS