Bone marrow mesenchymal stem cell-secreted exosomes carrying microRNA-125b protect against myocardial ischemia reperfusion injury via targeting SIRT7

BMSCs protect against renal ischemia-reperfusion injury by secreting exosomes loaded with miR-199a-5p that target BIP to inhibit endoplasmic reticulum stress at the very early reperfusion stages

(2019) Chenyang Wang et al.   FASEB JOURNAL

Mesenchymal stromal cell-derived exosomes attenuate myocardial ischaemia-reperfusion injury through miR-182-regulated macrophage polarization

(2019) Jinxuan Zhao et al.   CARDIOVASCULAR RESEARCH

Sirtuin7 has an oncogenic potential via promoting the growth of cholangiocarcinoma cells

(2018) Wenzhi Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Transplanted Mesenchymal Stem Cells Reduce Autophagic Flux in Infarcted Hearts via the Exosomal Transfer of mir-125b

(2018) Changchen Xiao et al.   CIRCULATION RESEARCH

Cardiac-derived CTRP9 protects against myocardial ischemia/reperfusion injury via calreticulin-dependent inhibition of apoptosis

(2018) Dajun Zhao et al.   Cell Death & Disease

MicroRNA-132, Delivered by Mesenchymal Stem Cell-Derived Exosomes, Promote Angiogenesis in Myocardial Infarction

(2018) Teng Ma et al.   Stem Cells International

Sirtuin7 is involved in protecting neurons against oxygen-glucose deprivation and reoxygenation-induced injury through regulation of the p53 signaling pathway

(2017) Jianrui Lv et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Cardiac progenitor cell-derived exosomes prevent cardiomyocytes apoptosis through exosomal miR-21 by targeting PDCD4

(2016) J Xiao et al.   Cell Death & Disease

Sirt7 Contributes to Myocardial Tissue Repair by Maintaining Transforming Growth Factor-β Signaling PathwayCLINICAL PERSPECTIVE

(2015) Satoshi Araki et al.   CIRCULATION

The Protective Role of Interleukin-33 in Myocardial Ischemia and Reperfusion Is Associated with Decreased HMGB1 Expression and Up-Regulation of the P38 MAPK Signaling Pathway

(2015) Ma Ruisong et al.   PLoS One

Overexpression of the muscle-specific protein, melusin, protects from cardiac ischemia/reperfusion injury

(2014) Claudia Penna et al.   BASIC RESEARCH IN CARDIOLOGY

MicroRNA-125b protects against myocardial ischaemia/reperfusion injury via targeting p53-mediated apoptotic signalling and TRAF6

(2014) Xiaohui Wang et al.   CARDIOVASCULAR RESEARCH

Selective expression of tumor necrosis factor-related apoptosis-inducing ligand mediated by microRNA suppresses renal carcinoma growth

(2014) Zhuo Zhang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Anti-inflammatory effect of exendin-4 postconditioning during myocardial ischemia and reperfusion

(2014) Xianjin Du et al.   MOLECULAR BIOLOGY REPORTS

Etanercept Attenuates Myocardial Ischemia/Reperfusion Injury by Decreasing Inflammation and Oxidative Stress

(2014) Mei Yang et al.   PLoS One

Heparin-binding epidermal growth factor-like growth factor restores Wnt/β-catenin signaling in intestinal stem cells exposed to ischemia/reperfusion injury

(2014) Chun-Liang Chen et al.   SURGERY

Differential Effects of Trans and Polyunsaturated Fatty Acids on Ischemia/ Reperfusion Injury and its Associated Cardiovascular Disease States

(2013) Riya Ganguly et al.   CURRENT PHARMACEUTICAL DESIGN

Allogeneic bone marrow-derived mesenchymal stem cells attenuate hepatic ischemia-reperfusion injury by suppressing oxidative stress and inhibiting apoptosis in rats

(2013) GUANGXIN JIN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Myocardial ischemia-reperfusion injury: a neglected therapeutic target

(2013) Derek J. Hausenloy et al.   JOURNAL OF CLINICAL INVESTIGATION

Bone-marrow mesenchymal stem cells reduce rat intestinal ischemia-reperfusion injury, ZO-1 downregulation and tight junction disruptionviaa TNF-α-regulated mechanism

(2013) Zhong-Yang Shen   WORLD JOURNAL OF GASTROENTEROLOGY

MicroRNA-15a/b are up-regulated in response to myocardial ischemia/reperfusion injury

(2012) Liu Li-Feng et al.   Journal of Geriatric Cardiology

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

MicroRNA-494 Targeting Both Proapoptotic and Antiapoptotic Proteins Protects Against Ischemia/Reperfusion-Induced Cardiac Injury

(2010) Xiaohong Wang et al.   CIRCULATION

Circulating MicroRNAs in Patients With Coronary Artery Disease

(2010) Stephan Fichtlscherer et al.   CIRCULATION RESEARCH

The role of microRNA in modulating myocardial ischemia-reperfusion injury

(2010) Yumei Ye et al.   PHYSIOLOGICAL GENOMICS

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

(2010) Ruenn Chai Lai et al.   Stem Cell Research

MicroRNA-320 Is Involved in the Regulation of Cardiac Ischemia/Reperfusion Injury by Targeting Heat-Shock Protein 20

(2009) Xiao-Ping Ren et al.   CIRCULATION

Bone Marrow Mesenchymal Stem Cells Reduce Intestinal Ischemia/Reperfusion Injuries in Rats

(2009) Haitao Jiang et al.   JOURNAL OF SURGICAL RESEARCH

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

(2008) Olesya Vakhrusheva et al.   CIRCULATION RESEARCH

Toward MicroRNA–Based Therapeutics for Heart Disease

(2008) Eva van Rooij et al.   CIRCULATION RESEARCH