Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

(2019) Richard Karlsson Linnér et al.   NATURE GENETICS

Identification of common genetic risk variants for autism spectrum disorder

(2019) Jakob Grove et al.   NATURE GENETICS

Cohort Profile: The National Longitudinal Study of Adolescent to Adult Health (Add Health)

(2019) Kathleen Mullan Harris et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum

(2018) Andrea Ganna et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder

(2018) Joanna Martin et al.   BIOLOGICAL PSYCHIATRY

Transformation of Summary Statistics from Linear Mixed Model Association on All-or-None Traits to Odds Ratio

(2018) Luke R. Lloyd-Jones et al.   GENETICS

Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero

(2018) Nicole M Warrington et al.   HUMAN MOLECULAR GENETICS

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

Multi-trait analysis of genome-wide association summary statistics using MTAG

(2018) Patrick Turley et al.   NATURE GENETICS

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

(2018) Antonio F. Pardiñas et al.   NATURE GENETICS

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

(2018) Hilary K. Finucane et al.   NATURE GENETICS

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

Transformation of Summary Statistics from Linear Mixed Model Association on All-or-None Traits to Odds Ratio

(2018) Luke R. Lloyd-Jones et al.   GENETICS

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia

(2018) Joëlle A. Pasman et al.   NATURE NEUROSCIENCE

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

(2018) Ditte Demontis et al.   NATURE GENETICS

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

(2017) T-K Clarke et al.   MOLECULAR PSYCHIATRY

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections

(2017) Chao Tian et al.   Nature Communications

Sex Hormones and Hair Loss in Men From the General Population of Northeastern Germany

(2017) Hanna Kische et al.   JAMA Dermatology

Genome-Wide Association Study of Male Sexual Orientation

(2017) Alan R. Sanders et al.   Scientific Reports

Disease and Polygenic Architecture: Avoid Trio Design and Appropriately Account for Unscreened Control Subjects for Common Disease

(2016) Wouter J. Peyrot et al.   AMERICAN JOURNAL OF HUMAN GENETICS

RVTESTS: an efficient and comprehensive tool for rare variant association analysis using sequence data: Table 1.

(2016) Xiaowei Zhan et al.   BIOINFORMATICS

Sexual orientation and symptoms of common mental disorder or low wellbeing: combined meta-analysis of 12 UK population health surveys

(2016) Joanna Semlyen et al.   BMC Psychiatry

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

(2016) William J. Astle et al.   CELL

SNP array screening of cryptic genomic imbalances in 450 Japanese subjects with intellectual disability and multiple congenital anomalies previously negative for large rearrangements

(2016) Daniela Tiaki Uehara et al.   JOURNAL OF HUMAN GENETICS

Meta-analysis of genome-wide association studies of anxiety disorders

(2016) T Otowa et al.   MOLECULAR PSYCHIATRY

Genome-wide associations for birth weight and correlations with adult disease

(2016) Momoko Horikoshi et al.   NATURE

Genome-wide association study identifies 74 loci associated with educational attainment

(2016) Aysu Okbay et al.   NATURE

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

(2016) Aysu Okbay et al.   NATURE GENETICS

Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders

(2016) Min-Tzu Lo et al.   NATURE GENETICS

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

(2016) Nicola Barban et al.   NATURE GENETICS

Detection and interpretation of shared genetic influences on 42 human traits

(2016) Joseph K Pickrell et al.   NATURE GENETICS

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

Integrative approaches for large-scale transcriptome-wide association studies

(2016) Alexander Gusev et al.   NATURE GENETICS

The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)

(2016) Jacqueline MacArthur et al.   NUCLEIC ACIDS RESEARCH

Genetics of complex traits: prediction of phenotype, identification of causal polymorphisms and genetic architecture

(2016) M. E. Goddard et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

(2015) Bjarni J. Vilhjálmsson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

(2015) Felix R Day et al.   NATURE GENETICS

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Efficient Bayesian mixed-model analysis increases association power in large cohorts

(2015) Po-Ru Loh et al.   NATURE GENETICS

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

(2015) Thomas W. Winkler et al.   PLoS Genetics

The National Longitudinal Study of Adolescent to Adult Health (Add Health) Sibling Pairs Genome-Wide Data

(2014) Matthew B. McQueen et al.   BEHAVIOR GENETICS

A genome-wide association study of anorexia nervosa

(2014) V Boraska et al.   MOLECULAR PSYCHIATRY

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

(2014) John R. B. Perry et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

A framework for the interpretation of de novo mutation in human disease

(2014) Kaitlin E Samocha et al.   NATURE GENETICS

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

Genome-wide scan demonstrates significant linkage for male sexual orientation

(2014) A. R. Sanders et al.   PSYCHOLOGICAL MEDICINE

Reproduction, Smell, and Neurodevelopmental Disorders: Genetic Defects in Different Hypogonadotropic Hypogonadal Syndromes

(2014) Hernan Valdes-Socin et al.   Frontiers in Endocrinology

A Mendelian Trait for Olfactory Sensitivity Affects Odor Experience and Food Selection

(2013) Sara R. Jaeger et al.   CURRENT BIOLOGY

Identification of Regions Associated with Variation in Sensitivity to Food-Related Odors in the Human Genome

(2013) Jeremy F. McRae et al.   CURRENT BIOLOGY

Neural control of sexually dimorphic behaviors

(2013) Devanand S Manoli et al.   CURRENT OPINION IN NEUROBIOLOGY

Changes in sexual attitudes and lifestyles in Britain through the life course and over time: findings from the National Surveys of Sexual Attitudes and Lifestyles (Natsal)

(2013) Catherine H Mercer et al.   LANCET

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

(2013) Joshua C. Randall et al.   PLoS Genetics

Genome-Wide Association Study of Multiplex Schizophrenia Pedigrees

(2012) Douglas F. Levinson et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genetic architectures of psychiatric disorders: the emerging picture and its implications

(2012) Patrick F. Sullivan et al.   NATURE REVIEWS GENETICS

Synergistic Effect of SRY and Its Direct Target, WDR5, on Sox9 Expression

(2012) Zhen Xu et al.   PLoS One

A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone–Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation

(2012) Andrea D. Coviello et al.   PLoS Genetics

Fecundity of Patients With Schizophrenia, Autism, Bipolar Disorder, Depression, Anorexia Nervosa, or Substance Abuse vs Their Unaffected Siblings

(2012) Robert A. Power et al.   JAMA Psychiatry

Estimating Missing Heritability for Disease from Genome-wide Association Studies

(2011) Sang Hong Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

(2011)   NATURE GENETICS

Basic Helix-Loop-Helix Transcription Factor TCF21 Is a Downstream Target of the Male Sex Determining Gene SRY

(2011) Ramji K. Bhandari et al.   PLoS One

The Internet-Based MGS2 Control Sample: Self Report of Mental Illness

(2010) Alan R. Sanders et al.   AMERICAN JOURNAL OF PSYCHIATRY

Robust relationship inference in genome-wide association studies

(2010) Ani Manichaikul et al.   BIOINFORMATICS

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations

(2010) J. C. Denny et al.   BIOINFORMATICS

Meta-analysis of genome-wide association studies for personality

(2010) M H M de Moor et al.   MOLECULAR PSYCHIATRY

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

(2010)   NATURE GENETICS

GWAF: an R package for genome-wide association analyses with family data

(2009) Ming-Huei Chen et al.   BIOINFORMATICS

The degradation of (all-E)-β-carotene by cigarette smoke

(2009) Gordon M. Lowe et al.   FREE RADICAL RESEARCH

Common variants on chromosome 6p22.1 are associated with schizophrenia

(2009) Jianxin Shi et al.   NATURE

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Effects of dependence in high-dimensional multiple testing problems

(2008) Kyung In Kim et al.   BMC BIOINFORMATICS