Superparamagnetic Iron Oxide Nanoparticles—Current and Prospective Medical Applications

MRI-Visible siRNA Nanomedicine Directing Neuronal Differentiation of Neural Stem Cells in Stroke

(2018) Liejing Lu et al.   ADVANCED FUNCTIONAL MATERIALS

PPARs are mediators of anti-cancer properties of superparamagnetic iron oxide nanoparticles (SPIONs) functionalized with conjugated linoleic acid

(2018) Marina Ricci et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Rationally designed magnetic nanoparticles as anticoagulants for blood purification

(2018) Weifeng Zhao et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Magnetic Resonance Imaging of Sentinel Lymph Nodes Using Intraprostatic Injection of Superparamagnetic Iron Oxide Nanoparticles in Prostate Cancer Patients: First-in-human Results

(2018) Alexander Winter et al.   EUROPEAN UROLOGY

Dextran-coated superparamagnetic iron oxide nanoparticles for magnetic resonance imaging: evaluation of size-dependent imaging properties, storage stability and safety

(2018) Harald Unterweger et al.   International Journal of Nanomedicine

Uptake and bioreactivity of charged chitosan-coated superparamagnetic nanoparticles as promising contrast agents for magnetic resonance imaging

(2018) Gabriela Kania et al.   Nanomedicine-Nanotechnology Biology and Medicine

Surface Modifications of Nanoparticles for Stability in Biological Fluids

(2018) Luca Guerrini et al.   Materials

SPION-Enhanced Magnetic Resonance Imaging of Alzheimer's Disease Plaques in AβPP/PS-1 Transgenic Mouse Brain

(2018) Laurel O. Sillerud et al.   JOURNAL OF ALZHEIMERS DISEASE

The world’s strongest MRI machines are pushing human imaging to new limits

(2018) Anna Nowogrodzki   NATURE

Human mesenchymal stem cell-derived iron oxide exosomes allow targeted ablation of tumor cells via magnetic hyperthermia

(2017) Ursula Altanerova et al.   International Journal of Nanomedicine

Neural stem cell transplantation in ischemic stroke: A role for preconditioning and cellular engineering

(2017) Joshua D Bernstock et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Anti-Epidermal Growth Factor Receptor Aptamer and Antibody Conjugated SPIONs Targeted to Breast Cancer Cells: A Comparative Approach

(2017) Lutfiye Tutkun et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Superparamagnetic iron oxide nanoparticles conjugated with folic acid for dual target-specific drug delivery and MRI in cancer theranostics

(2017) Yinping Huang et al.   Materials Science & Engineering C-Materials for Biological Applications

A polymeric temozolomide nanocomposite against orthotopic glioblastoma xenograft: tumor-specific homing directed by nestin

(2017) Suma Prabhu et al.   Nanoscale

Highly versatile SPION encapsulated PLGA nanoparticles as photothermal ablators of cancer cells and as multimodal imaging agents

(2017) Balasubramanian Sivakumar et al.   Biomaterials Science

In Vivo Imaging of Local Gene Expression Induced by Magnetic Hyperthermia

(2017) Olivier Sandre et al.   Genes

Magnetic Particle Imaging (MPI): Experimental Quantification of Vascular Stenosis Using Stationary Stenosis Phantoms

(2017) Sarah Vaalma et al.   PLoS One

Bio-identity and fate of albumin-coated SPIONs evaluated in cells and by the C. elegans model

(2016) Si-Ming Yu et al.   Acta Biomaterialia

Mitochondrial electron transport chain identified as a novel molecular target of SPIO nanoparticles mediated cancer-specific cytotoxicity

(2016) Chengyong He et al.   BIOMATERIALS

Theranostic MUC-1 aptamer targeted gold coated superparamagnetic iron oxide nanoparticles for magnetic resonance imaging and photothermal therapy of colon cancer

(2016) Morteza Azhdarzadeh et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

PSMA targeted docetaxel-loaded superparamagnetic iron oxide nanoparticles for prostate cancer

(2016) Prashanth K.B. Nagesh et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Co-precipitation of DEAE-dextran coated SPIONs: how synthesis conditions affect particle properties, stem cell labelling and MR contrast

(2016) Michael Barrow et al.   Contrast Media & Molecular Imaging

Hyaluronan-modified superparamagnetic iron oxide nanoparticles for bimodal breast cancer imaging and photothermal therapy

(2016) Rui-Meng Yang et al.   International Journal of Nanomedicine

Poly-paclitaxel/cyclodextrin-SPION nano-assembly for magnetically guided drug delivery system

(2016) Hyeonjeong Jeon et al.   JOURNAL OF CONTROLLED RELEASE

Clinically Approved Nanoparticle Imaging Agents

(2016) A. S. Thakor et al.   JOURNAL OF NUCLEAR MEDICINE

Superparamagnetic iron-oxide nanoparticles mPEG350– and mPEG2000-coated: cell uptake and biocompatibility evaluation

(2016) Adny H. Silva et al.   Nanomedicine-Nanotechnology Biology and Medicine

Albumin-coated SPIONs: an experimental and theoretical evaluation of protein conformation, binding affinity and competition with serum proteins

(2016) Siming Yu et al.   Nanoscale

Overendocytosis of superparamagnetic iron oxide particles increases apoptosis and triggers autophagic cell death in human osteosarcoma cell under a spinning magnetic field

(2016) Shaohua Du et al.   Oncotarget

Novel nanostructural contrast for magnetic resonance imaging of endothelial inflammation: targeting SPIONs to vascular endothelium

(2016) Agnieszka Kaczyńska et al.   RSC Advances

Magnetic nanoparticle-based drug delivery for cancer therapy

(2015) Rainer Tietze et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pre-operative sentinel lymph node localization in breast cancer with superparamagnetic iron oxide MRI: the SentiMAG Multicentre Trial imaging subprotocol

(2015) Joost J Pouw et al.   BRITISH JOURNAL OF RADIOLOGY

Magnetic particle imaging: current developments and future directions

(2015) Nikolaos Panagiotopoulos et al.   International Journal of Nanomedicine

Hypericin-bearing magnetic iron oxide nanoparticles for selective drug delivery in photodynamic therapy

(2015) Harald Unterweger et al.   International Journal of Nanomedicine

70-kDa heat shock protein coated magnetic nanocarriers as a nanovaccine for induction of anti-tumor immune response in experimental glioma

(2015) Maxim A. Shevtsov et al.   JOURNAL OF CONTROLLED RELEASE

The Dartmouth Center for Cancer Nanotechnology Excellence: magnetic hyperthermia

(2015) Ian Baker et al.   Nanomedicine

Ionizing radiation improves glioma-specific targeting of superparamagnetic iron oxide nanoparticles conjugated with cmHsp70.1 monoclonal antibodies (SPION–cmHsp70.1)

(2015) Maxim A. Shevtsov et al.   Nanoscale

Nanoparticles in endothelial theranostics

(2015) Szczepan Zapotoczny et al.   Pharmacological Reports

The In-Vivo Use of Superparamagnetic Iron Oxide Nanoparticles to Detect Inflammation Elicits a Cytokine Response but Does Not Aggravate Experimental Arthritis

(2015) Eline A. Vermeij et al.   PLoS One

Combined Preclinical Magnetic Particle Imaging and Magnetic Resonance Imaging: Initial Results in Mice

(2015) M. Kaul et al.   ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN

Stem cells labeled with superparamagnetic iron oxide nanoparticles in a preclinical model of cerebral ischemia: a systematic review with meta-analysis

(2015) Leopoldo P Nucci et al.   Stem Cell Research & Therapy

Tailoring the surface charge of dextran-based polymer coated SPIONs for modulated stem cell uptake and MRI contrast

(2015) Michael Barrow et al.   Biomaterials Science

Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy

(2015) Saji Uthaman et al.   Biomed Research International

Monoclonal Antibody–Conjugated Superparamagnetic Iron Oxide Nanoparticles for Imaging of Epidermal Growth Factor Receptor–Targeted Cells and Gliomas

(2015) Ketao Mu et al.   Molecular Imaging

Dynamic Magnetic Fields Remote-Control Apoptosis via Nanoparticle Rotation

(2014) Enming Zhang et al.   ACS Nano

Magnetic properties of hematite (α-Fe 2 O 3 ) nanoparticles prepared by hydrothermal synthesis method

(2014) Marin Tadic et al.   APPLIED SURFACE SCIENCE

MRI Meets MPI: A Bimodal MPI-MRI Tomograph

(2014) Patrick Vogel et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Superparamagnetic iron oxide nanoparticles conjugated with epidermal growth factor (SPION–EGF) for targeting brain tumors

(2014) Shevtsov et al.   International Journal of Nanomedicine

T1–T2 Dual-modal MRI contrast agents based on superparamagnetic iron oxide nanoparticles with surface attached gadolinium complexes

(2014) Agnieszka Szpak et al.   JOURNAL OF NANOPARTICLE RESEARCH

Protein Corona Composition of Superparamagnetic Iron Oxide Nanoparticles with Various Physico-Chemical Properties and Coatings

(2014) Usawadee Sakulkhu et al.   Scientific Reports

Sentinel Node Biopsy Using a Magnetic Tracer Versus Standard Technique: The SentiMAG Multicentre Trial

(2013) Michael Douek et al.   ANNALS OF SURGICAL ONCOLOGY

Magnetic Iron Oxide Nanoparticles for Multimodal Imaging and Therapy of Cancer

(2013) Reju Thomas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Application of magnetic field hyperthermia and superparamagnetic iron oxide nanoparticles to HIV-1-specific T-cell cytotoxicity

(2013) James Williams et al.   International Journal of Nanomedicine

Thermal potentiation of chemotherapy by magnetic nanoparticles

(2013) Madeline Torres-Lugo et al.   Nanomedicine

Iron Oxide Nanoparticle-Micelles (ION-Micelles) for Sensitive (Molecular) Magnetic Particle Imaging and Magnetic Resonance Imaging

(2013) Lucas W. E. Starmans et al.   PLoS One

Folate–PEG–superparamagnetic iron oxide nanoparticles for lung cancer imaging

(2012) Mi-Kyong Yoo et al.   Acta Biomaterialia

Highly efficient magnetic stem cell labeling with citrate-coated superparamagnetic iron oxide nanoparticles for MRI tracking

(2012) Kristin Andreas et al.   BIOMATERIALS

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Preparation andin vitroevaluation of folate-receptor-targeted SPION–polymer micelle hybrids for MRI contrast enhancement in cancer imaging

(2012) Shveta Mahajan et al.   NANOTECHNOLOGY

Aptamers and Their Biological Applications

(2012) Kyung-Mi Song et al.   SENSORS

Cancer hyperthermia using magnetic nanoparticles

(2011) Takeshi Kobayashi   Biotechnology Journal

Noninvasive cell-tracking methods

(2011) Moritz F. Kircher et al.   Nature Reviews Clinical Oncology

Evaluation of brain tumor vessels specific contrast agents for glioblastoma imaging

(2011) Boguslaw Tomanek et al.   NEURO-ONCOLOGY

The internalization pathway, metabolic fate and biological effect of superparamagnetic iron oxide nanoparticles in the macrophage-like RAW264.7 cell

(2011) JingLi Gu et al.   Science China-Life Sciences

Effects of Nanoparticle Size on Cellular Uptake and Liver MRI with Polyvinylpyrrolidone-Coated Iron Oxide Nanoparticles

(2010) Jing Huang et al.   ACS Nano

Amine-Functionalized Magnetic Nanoparticles for Rapid Capture and Removal of Bacterial Pathogens

(2010) Yan-Feng Huang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Magnetic nanoparticle hyperthermia for prostate cancer

(2010) Manfred Johannsen et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Concentration-dependent toxicity of iron oxide nanoparticles mediated by increased oxidative stress

(2010) Naqvi et al.   International Journal of Nanomedicine

Gold hybrid nanoparticles for targeted phototherapy and cancer imaging

(2010) Dickson K Kirui et al.   NANOTECHNOLOGY

Effect of Fe3O4magnetic nanoparticles on lysozyme amyloid aggregation

(2010) Andrea Bellova et al.   NANOTECHNOLOGY

The promotion of human mesenchymal stem cell proliferation by superparamagnetic iron oxide nanoparticles

(2009) Dong-Ming Huang et al.   BIOMATERIALS

Nanoparticles functionalised with recombinant single chain Fv antibody fragments (scFv) for the magnetic resonance imaging of cancer cells

(2009) Kim L. Vigor et al.   BIOMATERIALS

Nanocarriers’ entry into the cell: relevance to drug delivery

(2009) Hervé Hillaireau et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A new approach for the in vitro identification of the cytotoxicity of superparamagnetic iron oxide nanoparticles

(2009) Morteza Mahmoudi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Dexamethasone-containing biodegradable superparamagnetic microparticles for intra-articular administration: Physicochemical and magnetic properties, in vitro and in vivo drug release

(2009) Nicoleta Butoescu et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Anin vitrostudy of bare and poly(ethylene glycol)-co-fumarate-coated superparamagnetic iron oxide nanoparticles: a new toxicity identification procedure

(2009) Morteza Mahmoudi et al.   NANOTECHNOLOGY

Vancomycin-Modified Nanoparticles for Efficient Targeting and Preconcentration of Gram-Positive and Gram-Negative Bacteria

(2008) Arnold J. Kell et al.   ACS Nano

Stem cell therapy in stroke

(2008) F. Locatelli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

SPION-loaded chitosan–linoleic acid nanoparticles to target hepatocytes

(2008) Chang-Moon Lee et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Highly water-dispersible PEG surface modified ultra small superparamagnetic iron oxide nanoparticles useful for target-specific biomedical applications

(2008) Ja Young Park et al.   NANOTECHNOLOGY

Synthesis, properties, and applications of magnetic iron oxide nanoparticles

(2008) Amyn S. Teja et al.   PROGRESS IN CRYSTAL GROWTH AND CHARACTERIZATION OF MATERIALS