Melatonin and Docosahexaenoic Acid Decrease Proliferation of PNT1A Prostate Benign Cells via Modulation of Mitochondrial Bioenergetics and ROS Production

Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

(2017) Zhenhua Yang et al.   ONCOLOGY REPORTS

Mitochondrial Complex II: At the Crossroads

(2017) Ayenachew Bezawork-Geleta et al.   TRENDS IN BIOCHEMICAL SCIENCES

Chemoprevention of prostate cancer in men with high-grade prostatic intraepithelial neoplasia (HGPIN): a systematic review and adjusted indirect treatment comparison

(2017) Kang Cui et al.   Oncotarget

Role of Mitochondrial Reverse Electron Transport in ROS Signaling: Potential Roles in Health and Disease

(2017) Filippo Scialò et al.   Frontiers in Physiology

The Metabolic Phenotype of Prostate Cancer

(2017) Eric Eidelman et al.   Frontiers in Oncology

Loss of C/EBPδ enhances IR-induced cell death by promoting oxidative stress and mitochondrial dysfunction

(2016) Sudip Banerjee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Quantitative Proteomic Profiling Reveals That Diverse Metabolic Pathways Are Influenced by Melatonin in an in Vivo Model of Ovarian Carcinoma

(2016) Luiz Gustavo A. Chuffa et al.   JOURNAL OF PROTEOME RESEARCH

Melatonin enhances sensitivity to fluorouracil in oesophageal squamous cell carcinoma through inhibition of Erk and Akt pathway

(2016) Yun-Xin Lu et al.   Cell Death & Disease

Localization of MCT2 at peroxisomes is associated with malignant transformation in prostate cancer

(2015) Isabel Valença et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression

(2015) Julie V. Philley et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mitochondrial oncobioenergetic index: A potential biomarker to predict progression from indolent to aggressive prostate cancer

(2015) Praveen K. Vayalil et al.   Oncotarget

Influence of Melatonin on the Proliferative and Apoptotic Responses of the Prostate under Normal and Hyperglycemic Conditions

(2015) Marina G. Gobbo et al.   Journal of Diabetes Research

The Bioenergetic Health Index: a new concept in mitochondrial translational research

(2014) Balu K. Chacko et al.   CLINICAL SCIENCE

Melatonin improves mitochondrial function in inguinal white adipose tissue of Zücker diabetic fatty rats

(2014) Aroa Jimenéz-Aranda et al.   JOURNAL OF PINEAL RESEARCH

Effect of n-3 and n-6 unsaturated fatty acids on prostate cancer (PC-3) and prostate epithelial (RWPE-1) cells in vitro

(2013) Hongzhou Meng et al.   Lipids in Health and Disease

Bioenergetic and Antiapoptotic Properties of Mitochondria from Cultured Human Prostate Cancer Cell Lines PC-3, DU145 and LNCaP

(2013) Alexander Panov et al.   PLoS One

Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling

(2013) KUN-HUANG YAN et al.   Oncology Letters

The Omega-3 Polyunsaturated Fatty Acid DHA Induces Simultaneous Apoptosis and Autophagy via Mitochondrial ROS-Mediated Akt-mTOR Signaling in Prostate Cancer Cells Expressing Mutant p53

(2013) Soyeon Shin et al.   Biomed Research International

Mitochondrial complex II, a novel target for anti-cancer agents

(2012) Katarina Kluckova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Reduction of n-3 PUFAs, specifically DHA and EPA, and enhancement of peroxisomal beta-oxidation in type 2 diabetic rat heart

(2012) Lianguo Hou et al.   Cardiovascular Diabetology

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

Characterising the castration-resistant prostate cancer population: a systematic review

(2011) M. Kirby et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

O2 consumption rates along the growth curve: new insights into Trypanosoma cruzi mitochondrial respiratory chain

(2011) Thiago M. Silva et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Novel Role of Androgens in Mitochondrial Fission and Apoptosis

(2011) V. Choudhary et al.   MOLECULAR CANCER RESEARCH

Omega-3 Fatty Acid Inhibition of Prostate Cancer Progression to Hormone Independence Is Associated With Suppression of mTOR Signaling and Androgen Receptor Expression

(2011) William Friedrichs et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Monitoring intracellular melatonin levels in human prostate normal and cancer cells by HPLC

(2010) D. Hevia et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

(2010) Yohannes Mebratu et al.   CELL CYCLE

Mitochondrial dysfunction during in vitro hepatocyte steatosis is reversed by omega-3 fatty acid–induced up-regulation of mitofusin 2

(2010) Yong Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence

(2009) Sebastien Cagnol et al.   FEBS Journal

Membrane Potential Greatly Enhances Superoxide Generation by the Cytochromebc1Complex Reconstituted into Phospholipid Vesicles

(2009) Hagai Rottenberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission

(2009) Ruben K. Dagda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production

(2008) Ana López et al.   JOURNAL OF PINEAL RESEARCH