Dimethyl Fumarate ameliorates pulmonary arterial hypertension and lung fibrosis by targeting multiple pathways
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Dimethyl Fumarate ameliorates pulmonary arterial hypertension and lung fibrosis by targeting multiple pathways
Authors
Keywords
-
Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-02-02
DOI
10.1038/srep41605
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease
- (2015) Lauren E. Tebay et al. FREE RADICAL BIOLOGY AND MEDICINE
- Dimethyl Fumarate Inhibits the Nuclear Factor κB Pathway in Breast Cancer Cells by Covalent Modification of p65 Protein
- (2015) Irida Kastrati et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DMF, but not other fumarates, inhibits NF-κB activity in vitro in an Nrf2-independent manner
- (2015) Geoffrey O. Gillard et al. JOURNAL OF NEUROIMMUNOLOGY
- Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit
- (2015) Thomas Bertero et al. Cell Reports
- Dimethyl fumarate inhibits the expression and function of hypoxia-inducible factor-1α (HIF-1α)
- (2014) Guangzong Zhao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response
- (2014) Luca Azzolin et al. CELL
- Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension
- (2014) Marlene Rabinovitch et al. CIRCULATION RESEARCH
- The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease
- (2014) X. Varelas DEVELOPMENT
- Targeting the Wnt signaling pathways in pulmonary arterial hypertension
- (2014) Vinicio de Jesus Perez et al. DRUG DISCOVERY TODAY
- Adventitial Fibroblasts Induce a Distinct Proinflammatory/Profibrotic Macrophage Phenotype in Pulmonary Hypertension
- (2014) Karim C. El Kasmi et al. JOURNAL OF IMMUNOLOGY
- Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance
- (2014) L. Hecker et al. Science Translational Medicine
- Cellular, Pharmacological, and Biophysical Evaluation of Explanted Lungs from a Patient with Sickle Cell Disease and Severe Pulmonary Arterial Hypertension
- (2014) Natasha M. Rogers et al. Pulmonary Circulation
- Anticipated Classes of New Medications and Molecular Targets for Pulmonary Arterial Hypertension
- (2014) Nicholas W. Morrell et al. Pulmonary Circulation
- Endothelial GATA-6 Deficiency Promotes Pulmonary Arterial Hypertension
- (2013) Angela Ghatnekar et al. AMERICAN JOURNAL OF PATHOLOGY
- Considerations for Targeting β-Catenin Signaling in Fibrosis
- (2013) Cara J. Gottardi et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Updated Clinical Classification of Pulmonary Hypertension
- (2013) Gerald Simonneau et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- The Triterpenoid CDDO-Me Inhibits Bleomycin-Induced Lung Inflammation and Fibrosis
- (2013) Ajit A. Kulkarni et al. PLoS One
- Blocking Macrophage Leukotriene B4 Prevents Endothelial Injury and Reverses Pulmonary Hypertension
- (2013) W. Tian et al. Science Translational Medicine
- Survival and Predictors of Mortality in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension: Outcomes From the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma Registry
- (2013) Lorinda Chung et al. ARTHRITIS CARE & RESEARCH
- Cardiac-specific genetic inhibition of nuclear factor-κB prevents right ventricular hypertrophy induced by monocrotaline
- (2012) Sandeep Kumar et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- The Adventitia: Essential Regulator of Vascular Wall Structure and Function
- (2012) Kurt R. Stenmark et al. Annual Review of Physiology
- Bardoxolone Brings Nrf2-Based Therapies to Light
- (2012) Donna D. Zhang ANTIOXIDANTS & REDOX SIGNALING
- Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1
- (2012) Philip M. Bauer et al. CARDIOVASCULAR RESEARCH
- The Absence of Nrf2 Enhances NF-B-Dependent Inflammation following Scratch Injury in Mouse Primary Cultured Astrocytes
- (2012) Hao Pan et al. MEDIATORS OF INFLAMMATION
- Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis
- (2012) Ralf Gold et al. NEW ENGLAND JOURNAL OF MEDICINE
- Dimethylfumarate Attenuates Renal Fibrosis via NF-E2-Related Factor 2-Mediated Inhibition of Transforming Growth Factor-β/Smad Signaling
- (2012) Chang Joo Oh et al. PLoS One
- Angiotensin II induces skin fibrosis: a novel mouse model of dermal fibrosis
- (2012) Lukasz Stawski et al. ARTHRITIS RESEARCH & THERAPY
- A Novel Murine Model of Severe Pulmonary Arterial Hypertension
- (2011) Loredana Ciuclan et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Nuclear β-Catenin Is Increased in Systemic Sclerosis Pulmonary Fibrosis and Promotes Lung Fibroblast Migration and Proliferation
- (2011) Anna P. Lam et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Systemic Sclerosis-associated Pulmonary Arterial Hypertension
- (2010) Jérôme Le Pavec et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Inhibition of Wnt/ -catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis
- (2010) W. R. Henderson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure
- (2009) Kurt R. Stenmark et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Inflammation, Growth Factors, and Pulmonary Vascular Remodeling
- (2009) Paul M. Hassoun et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Thiazolidinediones Mimic Glucose Starvation in Facilitating Sp1 Degradation through the Up-Regulation of -Transducin Repeat-Containing Protein
- (2009) S. Wei et al. MOLECULAR PHARMACOLOGY
- Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis
- (2008) Wenge Li et al. BIOCHEMICAL PHARMACOLOGY
- Interleukin-6 Overexpression Induces Pulmonary Hypertension
- (2008) M. Kathryn Steiner et al. CIRCULATION RESEARCH
- Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies
- (2008) Ulrich Förstermann Nature clinical practice. Cardiovascular medicine
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started