Brachyury, Foxa2 and the cis-Regulatory Origins of the Notochord

Eukaryotic enhancers: common features, regulation, and participation in diseases

(2015) Maksim Erokhin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers

(2015) Denes Hnisz et al.   MOLECULAR CELL

Recurrent somatic mutations in regulatory regions of human cancer genomes

(2015) Collin Melton et al.   NATURE GENETICS

Notochord to Nucleus Pulposus Transition

(2015) Lisa Lawson et al.   Current Osteoporosis Reports

How was the notochord born?

(2015) Nori Satoh et al.   EVOLUTION & DEVELOPMENT

Looping Back to Leap Forward: Transcription Enters a New Era

(2014) Michael Levine et al.   CELL

An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element

(2014) M. R. Mansour et al.   SCIENCE

Tbx2/3 is an essential mediator within the Brachyury gene network during Ciona notochord development

(2013) D. S. Jose-Edwards et al.   DEVELOPMENT

Functional Brachyury Binding Sites Establish a Temporal Read-out of Gene Expression in the Ciona Notochord

(2013) Lavanya Katikala et al.   PLOS BIOLOGY

Parallel Evolution of Chordate Cis-Regulatory Code for Development

(2013) Laura Doglio et al.   PLoS Genetics

Genome-Wide Screens for In Vivo Tinman Binding Sites Identify Cardiac Enhancers with Diverse Functional Architectures

(2013) Hong Jin et al.   PLoS Genetics

A compact, in vivo screen of all 6-mers reveals drivers of tissue-specific expression and guides synthetic regulatory element design

(2013) Robin P Smith et al.   GENOME BIOLOGY

A cis-regulatory module upstream of deltaC regulated by Ntla and Tbx16 drives expression in the tailbud, presomitic mesoderm and somites

(2012) Leila Jahangiri et al.   DEVELOPMENTAL BIOLOGY

Identification of a rudimentary neural crest in a non-vertebrate chordate

(2012) Philip Barron Abitua et al.   NATURE

Genomic Targets of Brachyury (T) in Differentiating Mouse Embryonic Stem Cells

(2012) Amanda L. Evans et al.   PLoS One

A Novel Mammal-Specific Three Partite Enhancer Element Regulates Node and Notochord-Specific Noto Expression

(2012) Leonie Alten et al.   PLoS One

Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord

(2011) Owen J. Tamplin et al.   DEVELOPMENTAL BIOLOGY

The identification of transcription factors expressed in the notochord of Ciona intestinalis adds new potential players to the brachyury gene regulatory network

(2011) Diana S. José-Edwards et al.   DEVELOPMENTAL DYNAMICS

Transcriptional Enhancers in Animal Development and Evolution

(2010) Mike Levine   CURRENT BIOLOGY

Genomic cis-regulatory networks in the early Ciona intestinalis embryo

(2010) A. Kubo et al.   DEVELOPMENT

What Is a Microsatellite: A Computational and Experimental Definition Based upon Repeat Mutational Behavior at A/T and GT/AC Repeats

(2010) Yogeshwar D. Kelkar et al.   Genome Biology and Evolution

Temporal regulation of the muscle gene cascade by Macho1 and Tbx6 transcription factors in Ciona intestinalis

(2010) J. E. Kugler et al.   JOURNAL OF CELL SCIENCE

Early Chordate Origins of the Vertebrate Second Heart Field

(2010) A. Stolfi et al.   SCIENCE

Evolutionary Mirages: Selection on Binding Site Composition Creates the Illusion of Conserved Grammars in Drosophila Enhancers

(2010) Richard W. Lusk et al.   PLoS Genetics

A cis-Regulatory Signature for Chordate Anterior Neuroectodermal Genes

(2010) Maximilian Haeussler et al.   PLoS Genetics

Direct activation of a notochord cis-regulatory module by Brachyury and FoxA in the ascidian Ciona intestinalis

(2009) Y. J. Passamaneck et al.   DEVELOPMENT

The evolutionarily conserved leprecan gene: Its regulation by Brachyury and its role in the developing Ciona notochord

(2009) Matthew P. Dunn et al.   DEVELOPMENTAL BIOLOGY

Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus

(2009) C. J. Ott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The words of the regulatory code are arranged in a variable manner in highly conserved enhancers

(2008) Sepand Rastegar et al.   DEVELOPMENTAL BIOLOGY

Evolutionary conservation of vertebrate notochord genes in the ascidianCiona intestinalis

(2008) Jamie E. Kugler et al.   GENESIS