A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease

Analysis of common and coding variants with cardiovascular disease in the diabetes heart study

(2014) Jeremy N Adams et al.   Cardiovascular Diabetology

Polygenic Type 2 Diabetes Prediction at the Limit of Common Variant Detection

(2014) Jason L. Vassy et al.   DIABETES

Mendelian randomization studies in coronary artery disease

(2014) H. Jansen et al.   EUROPEAN HEART JOURNAL

Mendelian randomisation applied to drug development in cardiovascular disease: a review

(2014) Lauren E Mokry et al.   JOURNAL OF MEDICAL GENETICS

Effects of intensive glycaemic control on ischaemic heart disease: analysis of data from the randomised, controlled ACCORD trial

(2014) Hertzel C Gerstein et al.   LANCET

Insulin resistance and hyperglycaemia in cardiovascular disease development

(2014) Markku Laakso et al.   Nature Reviews Endocrinology

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

(2013) Joyce BJ van Meurs et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Predicting Risk of Type 2 Diabetes Mellitus with Genetic Risk Models on the Basis of Established Genome-wide Association Markers: A Systematic Review

(2013) Wei Bao et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

The shared allelic architecture of adiponectin levels and coronary artery disease

(2013) Zari Dastani et al.   ATHEROSCLEROSIS

The Canadian Diabetes Association 2013 Clinical Practice Guidelines—Raising the Bar and Setting Higher Standards!

(2013) Alice Y.Y. Cheng et al.   Canadian Journal of Diabetes

Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity

(2013) Antigone S. Dimas et al.   DIABETES

Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes

(2013) H. Yaghootkar et al.   DIABETES

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

(2013) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

Genetic Predisposition to Higher Blood Pressure Increases Coronary Artery Disease Risk

(2013) Wolfgang Lieb et al.   HYPERTENSION

Use of allele scores as instrumental variables for Mendelian randomization

(2013) Stephen Burgess et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis

(2013) S. Stender et al.   JOURNAL OF INTERNAL MEDICINE

Common variants associated with plasma triglycerides and risk for coronary artery disease

(2013) Ron Do et al.   NATURE GENETICS

Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts

(2013) T. M. Palmer et al.   BMJ-British Medical Journal

Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

(2013) Joshua C. Randall et al.   PLoS Genetics

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

(2013) Tove Fall et al.   PLOS MEDICINE

Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction

(2012) Anders Berg Jørgensen et al.   EUROPEAN HEART JOURNAL

Nonfasting Glucose, Ischemic Heart Disease, and Myocardial Infarction

(2012) Marianne Benn et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

(2012) Benjamin F Voight et al.   LANCET

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

(2012) Robert A Scott et al.   NATURE GENETICS

Basal Insulin and Cardiovascular and Other Outcomes in Dysglycemia

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

Mendelian Randomization: Application to Cardiovascular Disease

(2011) Nicholas J. Timpson et al.   CURRENT HYPERTENSION REPORTS

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

(2011) Heribert Schunkert et al.   NATURE GENETICS

Using multiple genetic variants as instrumental variables for modifiable risk factors

(2011) Tom M Palmer et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Pervasive Sharing of Genetic Effects in Autoimmune Disease

(2011) Chris Cotsapas et al.   PLoS Genetics

Genetically Elevated Apolipoprotein A-I, High-Density Lipoprotein Cholesterol Levels, and Risk of Ischemic Heart Disease

(2010) Christiane L. Haase et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies

(2010) The Emerging Risk Factors Collaboration   LANCET

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

The ACCORD Trial and Control of Blood Glucose Level in Type 2 Diabetes Mellitus

(2009) Stephen Havas   ARCHIVES OF INTERNAL MEDICINE

The 10-year post-trial follow-up of the United Kingdom Prospective Diabetes Study (UKPDS): cardiovascular observations in context

(2009) M Odette Gore et al.   Diabetes & Vascular Disease Research

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials

(2009) Kausik K Ray et al.   LANCET

SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap

(2008) A. D. Johnson et al.   BIOINFORMATICS

Management of cardiovascular disease in patients with diabetes: the 2008 Canadian Diabetes Association guidelines

(2008) O. K. Bhattacharyya et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Economic Costs of Diabetes in the U.S. in 2007

(2008)   DIABETES CARE

Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation

(2008) Nikolaos A Patsopoulos et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Intensive Glucose Lowering in Type 2 Diabetes

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Genetically Elevated C-Reactive Protein and Ischemic Vascular Disease

(2008) Jeppe Zacho et al.   NEW ENGLAND JOURNAL OF MEDICINE

Glucose Control and Vascular Complications in Veterans with Type 2 Diabetes

(2008) William Duckworth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study

(2008) Patrick Linsel-Nitschke et al.   PLoS One

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

(2007) Debbie A. Lawlor et al.   STATISTICS IN MEDICINE