Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors

Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase

(2013) J. M. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of MK-0941, a Novel Glucokinase Activator, on Glycemic Control in Insulin-Treated Patients With Type 2 Diabetes

(2011) G. E. Meininger et al.   DIABETES CARE

Discovery of (S)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type 2 Diabetes Mellitus

(2011) Jeffrey A. Pfefferkorn et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs

(2011) J.-i. Eiki et al.   MOLECULAR PHARMACOLOGY

Evolution of vertebrate glucokinase regulatory protein from a bacterialN-acetylmuramate 6-phosphate etherase

(2009) Maria Veiga-da-Cunha et al.   BIOCHEMICAL JOURNAL

Aqueous Process Chemistry: The Preparation of Aryl Sulfonyl Chlorides

(2009) Philip J. Hogan et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Glucokinase and molecular aspects of liver glycogen metabolism

(2008) Loranne Agius   BIOCHEMICAL JOURNAL

Glucokinase Activators for the Potential Treatment of Type 2 Diabetes

(2008) J. Grimsby et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Glucokinase activators in diabetes management

(2008) Matthew Coghlan et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Biophysical Characterization of the Interaction between Hepatic Glucokinase and Its Regulatory Protein

(2008) Oliver Anderka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY