Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning
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Title
Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning
Authors
Keywords
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Journal
NATURE BIOTECHNOLOGY
Volume 33, Issue 8, Pages 831-838
Publisher
Springer Nature
Online
2015-07-27
DOI
10.1038/nbt.3300
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- (2012) Gerrit M Daubner et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
- (2012) S. G. Landt et al. GENOME RESEARCH
- Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
- (2012) J. Wang et al. GENOME RESEARCH
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