Domestic Dogs and Cancer Research: A Breed-Based Genomics Approach

Cross Talk from Pets to People: Translational Osteosarcoma Treatments

(2013) S. J. Withrow et al.   ILAR JOURNAL

Genomic Medicine, Health Information Technology, and Patient Care

(2013) Christopher G. Chute et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Postmortem Evaluation of 435 Cases of Intracranial Neoplasia in Dogs and Relationship of Neoplasm with Breed, Age, and Body Weight

(2013) R.B. Song et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation

(2013) Guangwu Guo et al.   NATURE GENETICS

A COL11A2 Mutation in Labrador Retrievers with Mild Disproportionate Dwarfism

(2013) Mirjam Frischknecht et al.   PLoS One

Neutering Dogs: Effects on Joint Disorders and Cancers in Golden Retrievers

(2013) Gretel Torres de la Riva et al.   PLoS One

Missense Mutation in CAPN1 Is Associated with Spinocerebellar Ataxia in the Parson Russell Terrier Dog Breed

(2013) Oliver P. Forman et al.   PLoS One

A Frameshift Mutation in the Cubilin Gene (CUBN) in Border Collies with Imerslund-Gräsbeck Syndrome (Selective Cobalamin Malabsorption)

(2013) Marta Owczarek-Lipska et al.   PLoS One

Genome-Wide Association Study Identifies a Novel Canine Glaucoma Locus

(2013) Saija J. Ahonen et al.   PLoS One

Gene Expression Profiling of Histiocytic Sarcomas in a Canine Model: The Predisposed Flatcoated Retriever Dog

(2013) Kim M. Boerkamp et al.   PLoS One

A Copy Number Variant at the KITLG Locus Likely Confers Risk for Canine Squamous Cell Carcinoma of the Digit

(2013) Danielle M. Karyadi et al.   PLoS Genetics

The MTAP-CDKN2A Locus Confers Susceptibility to a Naturally Occurring Canine Cancer

(2012) A. L. Shearin et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Genome Analysis of the Domestic Dog (Korean Jindo) by Massively Parallel Sequencing

(2012) R. N. Kim et al.   DNA RESEARCH

The battle for sequencing supremacy

(2012) Michael Eisenstein   NATURE BIOTECHNOLOGY

Both Ends of the Leash — The Human Links to Good Dogs with Bad Genes

(2012) Elaine A. Ostrander   NEW ENGLAND JOURNAL OF MEDICINE

Identification of Quantitative Trait Loci (QTL) for Canine Hip Dysplasia and Canine Elbow Dysplasia in Bernese Mountain Dogs

(2012) Sophia Pfahler et al.   PLoS One

Identification of functionally active, low frequency copy number variants at 15q21.3 and 12q21.31 associated with prostate cancer risk

(2012) F. Demichelis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Landscape of Somatic Retrotransposition in Human Cancers

(2012) E. Lee et al.   SCIENCE

Variation in Genes Related to Cochlear Biology Is Strongly Associated with Adult-Onset Deafness in Border Collies

(2012) Jennifer S. Yokoyama et al.   PLoS Genetics

Molecular cytogenetic characterization of canine histiocytic sarcoma: A spontaneous model for human histiocytic cancer identifies deletion of tumor suppressor genes and highlights influence of genetic background on tumor behavior

(2011) Benoit Hedan et al.   BMC CANCER

A Hormone Sends Instant Messages to the Genome

(2011) Andreas Prokesch et al.   CELL

Characterization of canine osteosarcoma by array comparative genomic hybridization and RT-qPCR: Signatures of genomic imbalance in canine osteosarcoma parallel the human counterpart

(2011) Andrea Y. Angstadt et al.   GENES CHROMOSOMES & CANCER

Relative 8q gain predicts disease-specific survival irrespective of the TMPRSS2-ERG fusion status in diagnostic biopsies of prostate cancer

(2011) João D. Barros-Silva et al.   GENES CHROMOSOMES & CANCER

Current status of genome-wide association studies in cancer

(2011) Charles C. Chung et al.   HUMAN GENETICS

Epidemiology of surgical castration of dogs and cats in the United States

(2011) Rosalie Trevejo et al.   JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

(2011) John R Prensner et al.   NATURE BIOTECHNOLOGY

Of dogs and men: Comparative biology as a tool for the discovery of novel biomarkers and drug development targets in osteosarcoma

(2011) Kenneth S. Rankin et al.   PEDIATRIC BLOOD & CANCER

Dog models of naturally occurring cancer

(2011) Jennie L. Rowell et al.   TRENDS IN MOLECULAR MEDICINE

Man's Best Friend Becomes Biology's Best in Show: Genome Analyses in the Domestic Dog

(2010) Heidi G. Parker et al.   Annual Review of Genetics

Two New Cases of Polysomy 13 in Canine Prostate Cancer

(2010) N. Reimann-Berg et al.   CYTOGENETIC AND GENOME RESEARCH

Leading the way: canine models of genomics and disease

(2010) A. L. Shearin et al.   Disease Models & Mechanisms

A novel locus for canine osteosarcoma (OSA1) maps to CFA34, the canine orthologue of human 3q26

(2010) Jeffrey C. Phillips et al.   GENOMICS

Methods and mortality results of a health survey of purebred dogs in the UK

(2010) V. J. Adams et al.   JOURNAL OF SMALL ANIMAL PRACTICE

Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication

(2010) Bridgett M. vonHoldt et al.   NATURE

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Uncovering the roles of rare variants in common disease through whole-genome sequencing

(2010) Elizabeth T. Cirulli et al.   NATURE REVIEWS GENETICS

Tumor Transcriptome Sequencing Reveals Allelic Expression Imbalances Associated with Copy Number Alterations

(2010) Brian B. Tuch et al.   PLoS One

Data from the Danish Veterinary Cancer Registry on the occurrence and distribution of neoplasms in dogs in Denmark

(2010) L. B. Bronden et al.   VETERINARY RECORD

Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression

(2009) Melissa Paoloni et al.   BMC GENOMICS

Chromosome 8p Deletions and 8q Gains are Associated with Tumor Progression and Poor Prognosis in Prostate Cancer

(2009) A. T. El Gammal et al.   CLINICAL CANCER RESEARCH

Catching Cancer by the Tail: New Perspectives on the Use of Kinase Inhibitors

(2009) C. Khanna et al.   CLINICAL CANCER RESEARCH

Epidemiology, Pathology, and Genetics of Histiocytic Sarcoma in the Bernese Mountain Dog Breed

(2009) J. Abadie et al.   JOURNAL OF HEREDITY

Cancer Incidence in Pet Dogs: Findings of the Animal Tumor Registry of Genoa, Italy

(2009) D.F. Merlo et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Transcriptome sequencing to detect gene fusions in cancer

(2009) Christopher A. Maher et al.   NATURE

Leader of the pack: gene mapping in dogs and other model organisms

(2008) Elinor K. Karlsson et al.   NATURE REVIEWS GENETICS

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS