Generalized Multinucleate Cell Angiohistiocytoma, An Exceedingly Rare Entity

Authors

Nada Shaker¹ , Masoud Asgari² , Amour Khachemoune³ , Sepher Hamidi⁴

1. The Ohio State University
2. Yosemite medical group
3. NYU
4. UCLA

Conference / event

International Society of Dermatopathology Meeting 2022, May 2022 (Virtual)

Poster summary

Generalized form of multinucleate cell angiohistiocytoma is an exceedingly rare entity and mainly affects face, upper trunk and extremities. The most characteristic histopathologic features include a proliferation of small-sized capillary-type vessels in the superficial and mid dermis intermingled with sparse multinucleated fibrohistiocytic cells and lymphocytes, and dermal fibrosis with thickened collagen bundles. Dermatologists and pathologists should be aware of the generalized form of this entity and consider it in the differential diagnosis of maculopapular rashes that mainly involve upper chest and extremities. The clinicopathologic correlation and recognition of this variant remains essential to differentiate it from other mimickers.

Keywords

Generalized, Multinucleate cell angiohistocytoma, Fibrohistiocytic lesions

Research areas

Medicine

References

No data provided

Funding

No data provided

Supplemental files

No data provided

Additional information

Competing interests

No competing interests were disclosed.

Data availability statement

The datasets generated during and / or analyzed during the current study are available from the corresponding author on reasonable request.

Creative Commons license

Copyright © 2022 Shaker et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.