Primary Hyperparathyroidism: a Giant and Unusual Location of Parathyroid Adenoma

Authors

Zafer Pekkolay¹ , Hüsna Saraçoğlu¹ , Mehmet Turgut¹ , Mehmet Serdar Değirmenci¹ , Alpaslan Kemal Tuzcu¹

1. Dicle University, School of Medicine, Department of Endocrinology, Diyarbakır, Turkey

Conference / event

2.Dicle Dahiliye Kongresi, September 2022 (Virtual)

Poster summary

Aim: Solitary functioning parathyroid adenomas account for up to 90 percent of primary hyperparathyroidism. Parathyroid adenoma can sometimes be in unusual localization. Hypercalcemia was detected in the blood biochemistry of a 42-year-old woman who complained of nausea and vomiting. In the evaluation, a diagnosis of primary hyperparathyroidism was made. Labs: Calcium: 13,8 (8,8-10,6) mg/dl, Phosphorus: 2,7(2,5-4,5) mg/dl, Parathormone 404,3 (14-72) ng/L Neck Ultrasound: Giant parathyroid adenoma on the left of the neck Clinical course: 3000 ml/day saline and furosemide 40 mg/day were given for treating hypercalcemia. Localization was confirmed by parathyroid scintigraphy and the calcium level was reduced to 11,6 mg/dl with intravenous ibandronate. She was referred to surgery for parathyroid adenomectomy. Conclusion: Ectopic parathyroid adenoma may be localized in the thymus, carotid sheath, and retro-esophageal. Detailed neck ultrasonography makes it easier to find parathyroid adenoma.

Keywords

Primary hyperparathyroidism, Parathyroid adenoma, Giant, Unusual location

Research areas

Medicine

References

1. Clark Glasgow, Eunice Y C Lau, Luigi Aloj, Ines Harper, Heok Cheow, Tilak Das, Laurence Berman, Andrew S Powlson, Waiel A Bashari, Benjamin G Challis, Alison Marker, Penelope Moyle, Isra Ahmed Mohamed, Nadia Schoenmakers, Jonathan Broomfield, Sue Oddy, Carla Moran, Mark Gurnell, Piyush Jani, Liam Masterson, Brian Fish, Ruth T Casey, An Approach to a Patient With Primary Hyperparathyroidism and a Suspected Ectopic Parathyroid Adenoma, The Journal of Clinical Endocrinology & Metabolism, Volume 107

Funding

No data provided

Supplemental files

No data provided

Additional information

Competing interests

No competing interests were disclosed.

Data availability statement

The datasets generated during and / or analyzed during the current study are available from the corresponding author on reasonable request.

Creative Commons license

Copyright © 2022 Pekkolay et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.