Crazy 8 Initiative

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Grant Name

Crazy 8 Initiative

Funder

Alex's Lemonade Stand Foundation for Childhood Cancer (ALSF)

Country or Region

United States

Research Field

Brain Cancer

Cancer or Carcinogenesis

Cancer Therapies

Clinical Trials

Embryonic Structures

Immunotherapy

Leukemia & Other Blood Cancers

Pediatrics

Deadline

October 1, 2021 (Expired)

Grant Size

Upper $5,000,000USD Lower $1,000,000USD The budget for this award is between $1-5 million USD over four years. ALSF has committed $25 million to support the launch of The Crazy 8 Initiative.

Contact Info

Anna Greene, Director of Science a.greene@alexslemonade.org

Eligibility

- Applicants must have an MD, PhD, or MD/PhD or equivalent and be appointed as faculty (or equivalent) at an academic institution. - Applicants must have a track record of publication and funding productivity that should demonstrate that the project can be accomplished by the investigators.
- Applicant institutions may be based in the United States or abroad, and applicants need not be United States citizens. Funds must be granted to nonprofit institutions or organizations.

Description

The Crazy 8 Initiative Award will fund research into innovative and rigorous approaches that directly address the most intractable issues in pediatric cancer research today. This award is designed to coalesce cross-disciplinary cores of scientists working collaboratively in order to accelerate the pace of new cure discovery. The proposal should address a topic that is responsive to at least one of these four pediatric cancer research themes.1. Developmental Origins of Pediatric Cancers2. Drugging Currently Undruggable Pediatric Cancer Drivers3. Developing Novel Immunotherapies4. Discovery and Development of Novel Pediatric Cancer Drug TargetsIt is expected that successful applications will address one or more of the eight disciplines that formed the basis of the Crazy 8 initiative.1. Embryonal brain cancers2. High grade gliomas3. Fusion positive sarcomas4. Fusion negative sarcomas5. Leukemias6. Neuroblastoma7. Big data8. Catalyzing clinical trialsInvestigations may involve the exploration of a novel scientific hypothesis or the development of new model systems, tools or technologies that have the potential for significant impact on the field of childhood cancer. Collaboration and data sharing are a priority for this research program. We expect successful applications to propose multidisciplinary teams with a very clear plan for collaboration that would empower the study of big ideas that would not be easily addressable otherwise. Childhood cancer research applicants are encouraged to bring new, necessary expertise into the field. The awards will be judged on scientific soundness, significance and the potential for impact on improving the lives of children with cancer. Eligibility - Applicants must have an MD, PhD, or MD/PhD or equivalent and be appointed as faculty (or equivalent) at an academic institution. - Applicants must have a track record of publication and funding productivity that should demonstrate that the project can be accomplished by the investigators.
- Applicant institutions may be based in the United States or abroad, and applicants need not be United States citizens. Funds must be granted to nonprofit institutions or organizations.

Website

https://www.alexslemonade.org/crazy-8-initiative

Funding resources
Purdue Grant Writing Lab: Introduction to Grant Writing	Open Link
University of Wisconsin Writing Center: Planning and Writing a Grant Proposal	Open Link